I wanna chime in since I'll be 50 in 1 month. I'm 6' 276lbs (give or take a couple), and sit at 10-12% BF. I'm still quite vascular all over. I've been training since I was 20 years old and can honestly say I've never been bigger or stronger than I am now. I have the odd aches and pains popping up, elbows or knees once in a while, but overall am pretty happy with my continued progress. My attitude has always been, if you think your age is gonna make you slow down then it will. I don't think about my age and it hasn't been an issue yet. My biggest pet peeve is when a shitty looking 20 something comes up to me,and says"wow, you look good for your age." WTF. For my age? I look better than you at your age nimrod.