Arginine, ornithine and lysine are amino acids. They should work extremely well with glutamine, which is another amino acid. It is best to take it as a dietary supplement roughly 30 minutes before physical workout. Alternatively, it should be ingested on a relatively empty stomach either late in the evening or early in the morning. There are not any known side effects in the amounts taken, Arginine Ornithine Lysine is safe and effective.