Testosterone undecanoate

[wmk]

Anyone ever try test-u? It was being tested as a male contraceptive and clinical trials at 250mg/month makes it 99% effective. I never seen any of my reps carry this version of Test. I read that Test-u is like Test-E, but much slower in releasing. Has anyone ever seen Test-U in UG labs?

[Descimus]

nope hopefully one will start to produce some.

[dan12]

never seen it in any UG labs before. Personally I would just stick to test e, once a week injections are not that bad.

[Dk]

i dont really understand how test u works for a contraceptive any better then Test E.

its all the same test, the ester shouldnt change what it does to your body

[wmk]

I think that the test-e is shorter acting so some sperm may start producing again? They were using Test-u b/c it required only one shot/month. I been doing between 500-750mg of Test-e for the last few months, so my sperm is probably totally dead.

I guess your right DK, what is the difference other than having to inject the test-e in a few more times/month. I guess what made me feel comfortable about the Test-U is that clinical studies showed that it is 99% effective at a dose of one shot/month of 250mg. If I could read a study showing that Test-E is 99% effective, I would be a happy man!

[RagingRandy]

^^^^^ Here is the answer. For BB use it would not matter but for therapeutic use Test U is better.

Injectable testosterone undecanoate has more favourable pharmacokinetics and pharmacodynamics than testosterone enanthate
Carl-Joachim Partsch, Gerhard F Weinbauer, Ruiying Fang and Eberhard Nieschlag

Partsch C-J, Weinbauer GF, Fang R, Nieschlag E. Injectable testosterone undecanoate has more favourable pharmacokinetics and pharmacodynamics than testosterone enanthate. Eur J Endocrinol 1995;132:514–19. ISSN 0804–4643

Testosterone preparations producing constant physiological testosterone serum levels are desirable for long-term treatment of androgen deficiency. However, all injectable testosterone esters used clinically for substitution of male hypogonadism are characterized by unfavourable pharmacokinetics. We therefore tested two groups of five long-term orchidectomized cynomolgus monkeys (Macaca fascicularis), which received a single intramuscular injection of 10 mg/kg body weight of an injectable testosterone undecanoate (TU) preparation or testosterone enanthate (TE) in a preclinical study to assess the pharmacokinetic and pharmacodynamic characteristics of TU in comparison to TE. The dose was equivalent to 6.3 and 7.2 mg of pure testosterone per kilogram body weight in the TU and TE group, respectively. Following injection of TU, mean serum testosterone rose to 58 ± 18 nmol/l on day 1 and remained at moderately supraphysiological levels of 40–68 nmol/l for 45 days. Thereafter, testosterone levels were maintained in the normal range of intact monkeys for another 56 days. The TE injection resulted in highly supraphysiological levels of 100–177 nmol/l from immediately after the injection to day 5. A rapid decline followed and testosterone levels reached the lower limit of normal after 31 days. Serum testosterone levels were significantly higher in the TEthan in the TU-treated animals on days 0.5–7 (p < 0.05). Significantly lower testosterone levels were seen in the TE than in the TU group on days 16, 22, 25 and 31 (p < 0.05). Pharmacokinetic analysis of serum testosterone levels showed a significantly higher area under the curve for TU (4051 ± 939 vs 1771 ±208 nmol·h/l; p < 0.045), a longer residence time (40.7 ±4.1 vs 11.6 ±1.1 days; p <0.00012), a longer terminal half-life (25.7 ± 4.0 vs 10.3 ± 1.1 days; p < 0.0069), and a lower maximal testosterone concentration (73 ± 12 vs 177 ± 21 nmol/l; p < 0.0027). Following TU injection, oestradiol levels increased from 48 ± 8 pmol.l to a plateau of 80–118 pmol/l from day 1 to day 59. In contrast, TE injection resulted in a rapid increase of oestradiol levels to a maximum of 166 ± 29 pmol/l after 4 days (p < 0.05 vs TU- treated group). In the TU and TE groups levels below 80 pmol/l were reached after 66 and 16 days, respectively. Ejaculatory response was induced for 14 weeks in the TU animals in contrast to 7 weeks in the TE animals. Ejaculate weight reached a maximum of 533 ± 163 mg at day 52 in the TU group (p < 0.05 vs TE group). In the TE animals, the maximal ejaculate weight of 41 ± 17 mg was seen at day 16. Thus, with respect to androgen substitution therapy, TU showed pharmacokinetic and pharmacodynamic properties clearly superior to those of TE and may provide an important improvement in the substitution of male androgen deficiency and also for male contraception.

[wmk]

wow thanks for that RagingRandy!

Now only if some UG labs start making test-u :)

[St]

Not that great did the caps back in the day.

[ezturbo]

For bbing. Test is test is test. If you wanna contraceptive, strap a jimmy on or stuff estro down your girls throat. If you wanna permanently be sterile, and not have your boys snipped, get your hands on some progesterone and chemically castorate yourself. :D

Honestly, I've got a couple buddies get a ladyfriend prego while they were on. While they were on test, tren, couple orals. Male contraception is lame. Leave it up to the girl hah.

[natenator]

For bbing. Test is test is test. If you wanna contraceptive, strap a jimmy on or stuff estro down your girls throat. If you wanna permanently be sterile, and not have your boys snipped, get your hands on some progesterone and chemically castorate yourself. :D

Honestly, I've got a couple buddies get a ladyfriend prego while they were on. While they were on test, tren, couple orals. Male contraception is lame. Leave it up to the girl hah.
I agree. Not in my life would I ever risk relying on a steroid for protection. Then again, I am pretty horrible at using any sort of protection to begin with lmao.

[ezturbo]

I agree. Not in my life would I ever risk relying on a steroid for protection. Then again, I am pretty horrible at using any sort of protection to begin with lmao.

Hah I can picture all these little nates running around.

[natenator]

Hah I can picture all these little nates running around.
well I've never gotten a call yet so I am starting to wonder if my boys are swimming or not. lol

[wmk]

one problem with oral contraceptives for women is the killed sex drive. The study indicated that Test-u is 99% effective for males. That should be as safe as a condom. I wouldn't mind doing one shot of test-u a month along with my other cycles. According to some other articles that I read Test-U is quite a bit different than Test-p, test-e and test-c. The way it interacts and breaks downs in your body is what causes the sperm shut-down, even more so than the other forms of test.

The other problem is with condoms. I hate the ****ers.... If I wasn't married and still sleeping around they still have there use. But being married, I wouldn't mind taking a shot of test-u if it is 99% effective.

[RagingRandy]

I am going to ask my HRT doc about this. I won't be seeing him for a couple months though.

[Dk]

one problem with oral contraceptives for women is the killed sex drive. The study indicated that Test-u is 99% effective for males. That should be as safe as a condom. I wouldn't mind doing one shot of test-u a month along with my other cycles. According to some other articles that I read Test-U is quite a bit different than Test-p, test-e and test-c. The way it interacts and breaks downs in your body is what causes the sperm shut-down, even more so than the other forms of test.

The other problem is with condoms. I hate the ****ers.... If I wasn't married and still sleeping around they still have there use. But being married, I wouldn't mind taking a shot of test-u if it is 99% effective.

and even if it doesnt work.

nothing wrong with an extra 250mg of test a month, its not a lot, but it would be cheap as shit, and its extra, so might as well.

[AlbertaBeef]

I was doing 400mg a week of test u & 400mg of test e in some T400 I was using. Still got my woman pregnant so I don't think it's the esther

[Dk]

I was doing 400mg a week of test u & 400mg of test e in some T400 I was using. Still got my woman pregnant so I don't think it's the esther

do you mean 200 and 200?

and are you sure it wasnt Test D and Test E?

ive never seen Test U, or heard of it in a blend.

i wouldnt even want an ester longer then Test D

[Beachmuscle]

do you mean 200 and 200?

and are you sure it wasnt Test D and Test E?

ive never seen Test U, or heard of it in a blend.

i wouldnt even want an ester longer then Test D


Agreed, must be test Dec, not Undec.

Big difference.

[cdnsoldier]

Last time I tried Udec. was those red pills filled with oil. I got them from the Uk. This was a while back. I got zero out of it but then again the UK was notorious for fake pharm grade gear. Can't say they were real.

[z83]

Last time I tried Udec. was those red pills filled with oil. I got them from the Uk. This was a while back. I got zero out of it but then again the UK was notorious for fake pharm grade gear. Can't say they were real.

I had 3 boxes of the original Andriol directly from organon. It's a complete waste of time. 16-20 caps/day, nothing.

I don't remember where but i've seen those 4ml amps of undeca test

edit : NEBIDO 1000 mg/4ml,Testosterone Undecanoate...could be great

[AlbertaBeef]

do you mean 200 and 200?

and are you sure it wasnt Test D and Test E?

ive never seen Test U, or heard of it in a blend.

i wouldnt even want an ester longer then Test D


That's what the SA label said, maybe the swedes got it wrong? A few posts on this in the gear forum under SA. The blend was with 200 undecanoate & 200 e.