Clen VS Albuterol

[pinhead]

Which do you prefer and why? I shake too much on clen so I prefer albuterol though I find it a little weaker.

[St]

Were in the same boat pinhead,love clen better for fat loss,but the cramping from clen is bad,that is why albuterol is a little nicer for me.But i will give the edge to clen.

[Praetorian]

Which do you prefer and why? I shake too much on clen so I prefer albuterol though I find it a little weaker.

Albuterol is useless for fat burning...this has been debated to death.
P

[pinhead]

Albuterol is useless for fat burning...this has been debated to death.
P

Got any literature for that statement?

[Benny62]

I was getting crazy cramps from clen in my feet and calves from lots of running and cardio. I found supplementing with taurine very helpful.

[Praetorian]

Got any literature for that statement?
Do a search on almost any forum, Rxmuscle, MD, Razorripped, the list goes on. Talk a few people in teh know. There is more than substantial evidence and years of combined experience to back up that statement. As i said its a dead subject it has been debated to death. You want to waste your money be my guest.
P


From RXmuscle...question directed at Dave Palumbo.

"Dave- Im going to begin a cutting cycle and wondered what your thoughts were on Albuterol as a fat burner. I have tons of the stuff in different forms(inhaler,liquid)my brother used to have asthma. How much should i take and what is the best form to take it in. Basically how do i use the damn stuff.
Albuterol has virtually no fat burning potential so don't waste your time. If it did, the FDA would have banned it long ago."

[Body By Balco]

Salbutamol and Albuterol are the same compound.

Perhaps this abstract suggests that Albuterol can indeed increase energy expenditure and circulating FFA (aka thermogenesis).



Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E775-82. Epub 2003 Jun 24


Effect of beta1- and beta2-adrenergic stimulation on energy expenditure, substrate oxidation, and UCP3 expression in humans.

Hoeks J, van Baak MA, Hesselink MK, Hul GB, Vidal H, Saris WH, Schrauwen P.
NUTRIM, Department of Human Biology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. j.hoeks@hb.unimaas.nl

In humans, beta-adrenergic stimulation increases energy and fat metabolism. In the case of beta1-adrenergic stimulation, it is fueled by an increased lipolysis. We examined the effect of beta2-adrenergic stimulation, with and without a blocker of lipolysis, on thermogenesis and substrate oxidation. Furthermore, the effect of beta1-and beta2-adrenergic stimulation on uncoupling protein 3 (UCP3) mRNA expression was studied. Nine lean males received a 3-h infusion of dobutamine (DOB, beta1) or salbutamol (SAL, beta2). Also, we combined SAL with acipimox to block lipolysis (SAL+ACI). Energy and substrate metabolism were measured continuously, blood was sampled every 30 min, and muscle biopsies were taken before and after infusion. Energy expenditure significantly increased approximately 13% in all conditions. Fat oxidation increased 47 +/- 7% in the DOB group and 19 +/- 7% in the SAL group. but remained unchanged in the SAL+ACI condition. Glucose oxidation decreased 40 +/- 9% upon DOB, remained unchanged during SAL, and increased 27 +/- 11% upon SAL+ACI. Plasma free fatty acid (FFA) levels were increased by SAL (57 +/- 11%) and DOB (47 +/- 16%), whereas SAL+ACI caused about fourfold lower FFA levels compared with basal levels. No change in UCP3 was found after DOB or SAL, whereas SAL+ACI downregulated skeletal muscle UCP3 mRNA levels 38 +/- 13%. In conclusion, beta2-adrenergic stimulation directly increased energy expenditure independently of plasma FFA levels. Furthermore, this is the first study to demonstrate a downregulation of skeletal muscle UCP3 mRNA expression after the lowering of plasma FFA concentrations in humans, despite an increase in energy expenditure upon beta2-adrenergic stimulation.

PMID: 12824081 [PubMed - indexed for MEDLINE]

[Sean]

Albuterol is a waste of cash!! Had 2 bottles and I still have 3/4 of 1 left. Did basically nothing as a dieting aid!! Waste of money in my books..

[wmk]

I like albuterol as it has a shorter halflife, so sleeping at night is much easier. I started taking Lipo-Ex from ***** and it heats up really nice, in fact my face gets so hot and flushed that it is almost uncomfortable.

[Body By Balco]

Perhaps this explains why some people do not respond well to weaker beta 2 agonists like Albuterol. As well, and now related to what is below, there any many reasons at any given time that beta adrenoreceptor population density can vary.


ß2-Adrenergic Receptor Polymorphisms and Salbutamol-Stimulated Energy Expenditure

J. M. Oomen, C. T. M. van Rossum, B. Hoebee, W. H. M. Saris and M. A. van Baak
Department of Human Biology/NUTRIM (J.M.O., W.H.M.S., M.A.v.B.), Maastricht University, 6200 MD Maastricht, The Netherlands; and Department of Chronic Diseases Epidemiology (C.T.M.v.R.) and Laboratory of Health Effects Research (B.H.), National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands

Address all correspondence and requests for reprints to: J. M. Oomen, Department of Human Biology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands. E-mail: j.oomen@hb.unimaas.nl.

The ß-adrenergic system is involved in the control of energy metabolism and expenditure. The ß2-adrenergic receptor (ß2-AR) gene shows polymorphisms that have been associated with obesity in several studies. In vitro and in vivo studies suggest differences in ß2-AR-mediated function between these polymorphisms. The aim of this study was to investigate the influence of genetic variation in codon 16 of the ß2-AR gene on energy metabolism in humans.

Thirty-four subjects were recruited [Gly16Gly (n = 13), Gly16Arg (n = 16), or Arg16Arg (n = 5)]. The ß2-AR was stimulated with two doses of salbutamol (50 and 100 ng/kg fat-free mass per minute) after blockade of the ß1-adrenergic receptors with atenolol. Energy expenditure and plasma substrate and hormone concentrations were measured.

The increase in energy expenditure (EE) was significantly different among groups in which the Arg16Arg group showed the lowest increase (P < 0.05 vs. Gly carriers). In a multiple regression model, variations in the increase in nonesterified fatty acid concentration during salbutamol infusion (partial r = 0.51) and the polymorphism contributed significantly to the variation in EE. Thirty-five percent of the variation in EE was explained by these two factors.

We conclude that subjects with the Arg16Arg polymorphism of the &#223;2-AR gene have a reduced thermogenic response to &#223;2-adrenergic stimulation. Although this relatively small study needs confirmation, the findings support a role for this polymorphism in the development and maintenance of overweight and obesity.

[Rhinobolt10]

All I've ever gotten from clen is itchy... I've never really used it as effectively as I could though... looking back I just used it as a short cut and not one of the final things to add in after diet and cardio.

[rated_rko]

im gonna vote for clen on this one

[canadianmuscle0803]

there is simply no comparison, Clen hands down.