What Roids are DHT Based?

[Solo59]

My prostate can no longer take too much added DHT, but I do not intend to hang up my spurs, so was wondering which gear is especially high in DHT or derived from DHT. I know Masteron is one that is. Is Tren? Any help?

Solo

[L3]

anavar, winny

[natenator]

deca

[fathead]

anavar, winny

considering anavar is completely hair friendly i have doubts its dht derived.

winny yes. masteron yes. primo yes.

[nitrous]

considering anavar is completely hair friendly i have doubts its dht derived.

winny yes. masteron yes. primo yes.

anavar is DHT derived

[Bowlcut]

Masteron

[nitrous]

Masteron, Winstrol, Anavar, Primobolan, Proviron

[Beachmuscle]

Masteron, Winstrol, Anavar, Primobolan, Proviron

And of course test. :)

[Solo59]

anavar is DHT derived

From Wikipedia: "[Anavar] is not easily metabolised into DHT or estrogen." So whatever it's derived from, it does not raise DHT levels.

Solo

[Solo59]

And of course test. :)

:confused:Eh?

DHT is derived from Testosterone, not the other way round. See Wikipedia (http://en.wikipedia.org/wiki/Dihydrotestosterone), for example.

Solo

[nitrous]

From Wikipedia: "[Anavar] is not easily metabolised into DHT or estrogen." So whatever it's derived from, it does not raise DHT levels.

Solo

it is derived from DHT

"Since it is a derivative of DHT, Anavar is structurally..."
http://www.steroids-pharmacy.com/anavar-a-12.html


"Anavar is a mild anabolic with low androgenic activity. Its reduced androgenic activity is due to the fact that it is a derivative of dihydrotestosterone (DHT)"
http://www.ianavar.com/

[Beachmuscle]

:confused:Eh?

DHT is derived from Testosterone, not the other way round. See Wikipedia (http://en.wikipedia.org/wiki/Dihydrotestosterone), for example.

Solo

Ahh, gotcha, but doesn't Test raise DHT levels??????

[Kiem]

Yes Test raises DHT levels. Testosterone converts to DHT in your body via the 5alpha-Reductase enzyme. Just like how estrogen is raised as a result of conversion by aromatase enzyme.

Maybe you mean that if he wants to avoid DHT then he should also avoid test, since it converts to DHT. But he can block the conversion by taking drugs like finasteride.

[Vomit]

DHT = dihydrotestosterone. This refers to a reduction of the 4-5 double bond. A reduction of this bond does not necessarily make a compound a stronger binder to the AR receptor. Even if the compound does bind stronger then the parent compound this does not necessarily lead to greater androgenic effects

Example 1:
Anadrol
Anadrol is a oxymethylene derivative of 17-alpha methlydihydrotestosterone. It binds the androgen receptor so poorly that in the studies I have read the researchers could not detect binding (see Vida for full binding profiles of all anabolic steroids), however anadrol is a potent androgen, and causes a large amount of growth in mice prostate (the benchmark of androgenic potential).

Example 2:
Anavar
Anavar is a hetrocyclic DHT derivative with an oxygen incorperated into the 2 position of the A ring. Although anavar is a strong androgen the seperation between the anabolic effects and the androgenic effects allows a 10mg dose of anavar to be a decent anabolic while being a poor androgen. However at a larger dose anavar will exhibit the androgenic profile of a strong androgen.
The effect is dose depend as it is with all steroids

Example 3:
Testosterone
Testosterone is not a reduced compound but upon interaction with 5AR (5-alpha reducatase enzyme) becomes DHT. DHT is stronger then testosterone at binding the AR. So it is said by many authorities (sorry I dont have a reference) that test is androgenic because of DHT. This seems to be confirmed by the fact that 5AR inhibitors are very sucessful in prevenitng androgenic side effects like hair loss

Example 4:
Nandrolone
If testosterone exerts all its androgenic effects through conversion to DHT then it is easy to see why nandrolone is such a poor androgen. It gets converts to Dihydronandrolone which has poor binding the AR. Nandrolone itself binds roughly 3x as strongly as test to the AR (if memory serves me right). But since it is metabolized to DHN in scalp and prostate (tissues that have the highest concentration of 5AR), it makes a poor androgen.


These examples should illustrate that simply looking at the structure of a compound does not necessarily give you the ability to determine the androgenic profile - This is demonstrated by Anavar. Also even when it is known how strongly a compound binds the AR this does not necessarily let you know how androgenic it is (demonstrated by anadrol). Furthermore examples 4 and 5 illustrate that metabolism of steroid can have significant effects of how androgenic it is. Also anavar illustrates that dose is also an important factor as at a low dose a compound may have great anabolic effects with little to no androgenic effects, but at higher doses this relationship is lost.

I hope this has helped show how the structure activity relationship (or SAR as its called in pharmacology) is a complex thing.

My best advice to you is to get "Androgens and Anabolic Agents" by Vida. This text will provide you with the prostate growth potential of all anabolics studied to date.

As a quick reference steroids that contain the androstane skeleton (which is the 4-5 reduced steroid structure) are
Primobolon
Anadrol
Anavar
masteron
miotalan
stenbolone
proviron
winstrol

Steroids that are not 5-alpha reduced are
testosterone
halotestin
trenbolone
nandrolone
boldenone
dianabol

Both lists are not complete.

Sorry for all the spelling mistakes, I dont have time to clean this up and it should be quite obvious that Im not a english professor

[Solo59]

Thanks, uh, Vomit. Guess I'll go to Test & Tren rather than the Test & Mast i'm currently on (and unable to piss a lot of the time).

By the way, your writing was refreshingly sound, compared to so many on here.:tu

Solo

[Vomit]

My recommendation would be to take test and proscar. If you wanted you could also take deca by itself
http://en.wikipedia.org/wiki/Finasteride


You might need some viagra too as, DHT is responsible for erections and this cycle will pretty much eliminate it.

This cycle should have very low androgenic effects
I edited this as I was half asleep when I wrote it (6:00am) and I made some errors. Deca should not be taken with proscar.