GH to treat TBI or PCS

[turboturist]

I read a couple articles a while back that supported use of GH for the treatment of Traumatic Brain Injury and/or Post Concussion Syndrome.

Does anyone have any info or links that can confirm or dispute this? Medical studies preferably.

Or does any one have any input on this?

[big_luse]

I dont think its plays any part at all bro. Once a CNS neuron is destroyed via concussive force/damage of the meninges or the swelling of a concussion their gone for good.

That being said neurons in the PNS can regenerate --> but yeah. If this was the case you wouldnt see guys like Chuck, Wandy, and Nog getting punchy and slow in the tongue ... because you can bet your ass theyve all used GH for years. One of the most blatant examples is Phil Baroni - his recent interviews are depressing because its constant stuttering and mumbling, and hes one of the biggest sauce heads in the game.

[oharad]

I woudl also like info about GH to treat TBI's. In 2000 I took a brutal shot in the head in a MVA at around 120kms. Lost my peripheral vision on one side and concentration memory and irritability all became issues very quickly. Recently ran GH for 5 months.... I swear my vision in the peripherals improved, memory was better too!

most advances receded when i stopped the gh .... but u get the idea

[turboturist]

I dont think its plays any part at all bro. Once a CNS neuron is destroyed via concussive force/damage of the meninges or the swelling of a concussion their gone for good.

That being said neurons in the PNS can regenerate --> but yeah. If this was the case you wouldnt see guys like Chuck, Wandy, and Nog getting punchy and slow in the tongue ... because you can bet your ass theyve all used GH for years. One of the most blatant examples is Phil Baroni - his recent interviews are depressing because its constant stuttering and mumbling, and hes one of the biggest sauce heads in the game.

I am not talking about being punch drunk and all ****ed up already, more to prevent that. Most symptoms of PCS go away after a couple weeks, sometimes a couple months but their are 15% of the population that has the symptoms for several years (this is me) and some that show up later in life.

I had a doc appoint yesterday and we have been doing all kinds of tests trying to figure out why I have headaches, Dizziness, Fatigue, Irritability (with no reason for it), Insomnia, Loss of concentration and memory, and sensitivity to light and noise.

I have also noticed that I stutter sometimes now and I can not recall info as easily as before. And I have had some major concussions. One was 7 days in the hospital, one was 10 days in hospital, and the last one (that happened a few years ago) I still have 4 days of memory loss from and there are countless others that were not so serious.

I came across an issue of ESPN magazine a while back and cant find it, it had talked about some studies that have been done and there are giving GH to retired and current NFL players that have had PCS and TBI and it has helped with their symptoms.

This link is of a similar article but not quite the same one. So I am looking to see if some of this info they say is published is actually published or if it just shit in a mag.

http://www.brain-tumor.org/files/kelly_sportsinjury.pdf

The HG part starts on page 2.

[jsv22]

i did a quick search for you and this is what i found....it seems if there is a hGH deficiency post TBI you may benefit from therapy...if you want the full text to this i have access to it, just let me know

-jsv

Growth hormone deficient patients after traumatic brain injury - Baseline characteristics and benefits after growth hormone replacement - An analysis of the German KIMS database.
Kreitschmann-Andermahr I, Poll EM, Reineke A, Gilsbach JM, Brabant G, Buchfelder M, Faßbender W, Faust M, Kann PH, Wallaschofski H.

Department of Neurosurgery, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany.

OBJECTIVE: In recent years, traumatic brain injury (TBI) has been identified as a significant cause of growth hormone deficiency (GHD). The aim of the present study was to characterize adult TBI patients with GHD to elucidate the effect of human growth hormone (hGH) replacement in TBI patients as documented in the German Pfizer International Metabolic (KIMS) database. DESIGN: As of October 2006, 84 TBI patients had been included in the German KIMS database (n=28 childhood-onset and 54 adult-onset GHD). All 84 TBI patients were matched with 84 patients with GHD due to non-functioning pituitary adenoma (NFPA) also included in this database. Analysis of clinical and outcome variables was performed, with comparisons of childhood vs. adult TBI, and TBI vs. NFPA patients, at baseline and one-year follow-up. RESULTS: TBI patients with GHD were significantly younger at the onset of pituitary disease and exhibited a significantly longer time span between GHD diagnosis and KIMS entry than NFPA patients. Those KIMS patients who had sustained their TBI in childhood were of significantly shorter stature than adult-onset TBI patients. At 1-year follow-up, insulin-like growth factor I (IGF-I) standard deviation score levels had returned to the normal range and quality of life (QoL), as measured by QoL- Assessment of Growth Hormone Deficiency in Adults (AGHDA) questionnaire, improved significantly in TBI as in NFPA patients. CONCLUSION: This analysis provides preliminary data that TBI patients with GHD benefit from hGH replacement in terms of improved QoL in a similar fashion as do NFPA patients. Moreover, it suggests that belated diagnosis and treatment in childhood-onset GHD due to TBI might be related to a shorter final height in these children.

[turboturist]

Yes please I would like the full article. And anything else that may support it.


i did a quick search for you and this is what i found....it seems if there is a hGH deficiency post TBI you may benefit from therapy...if you want the full text to this i have access to it, just let me know

-jsv

Growth hormone deficient patients after traumatic brain injury - Baseline characteristics and benefits after growth hormone replacement - An analysis of the German KIMS database.
Kreitschmann-Andermahr I, Poll EM, Reineke A, Gilsbach JM, Brabant G, Buchfelder M, Faßbender W, Faust M, Kann PH, Wallaschofski H.

Department of Neurosurgery, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany.

OBJECTIVE: In recent years, traumatic brain injury (TBI) has been identified as a significant cause of growth hormone deficiency (GHD). The aim of the present study was to characterize adult TBI patients with GHD to elucidate the effect of human growth hormone (hGH) replacement in TBI patients as documented in the German Pfizer International Metabolic (KIMS) database. DESIGN: As of October 2006, 84 TBI patients had been included in the German KIMS database (n=28 childhood-onset and 54 adult-onset GHD). All 84 TBI patients were matched with 84 patients with GHD due to non-functioning pituitary adenoma (NFPA) also included in this database. Analysis of clinical and outcome variables was performed, with comparisons of childhood vs. adult TBI, and TBI vs. NFPA patients, at baseline and one-year follow-up. RESULTS: TBI patients with GHD were significantly younger at the onset of pituitary disease and exhibited a significantly longer time span between GHD diagnosis and KIMS entry than NFPA patients. Those KIMS patients who had sustained their TBI in childhood were of significantly shorter stature than adult-onset TBI patients. At 1-year follow-up, insulin-like growth factor I (IGF-I) standard deviation score levels had returned to the normal range and quality of life (QoL), as measured by QoL- Assessment of Growth Hormone Deficiency in Adults (AGHDA) questionnaire, improved significantly in TBI as in NFPA patients. CONCLUSION: This analysis provides preliminary data that TBI patients with GHD benefit from hGH replacement in terms of improved QoL in a similar fashion as do NFPA patients. Moreover, it suggests that belated diagnosis and treatment in childhood-onset GHD due to TBI might be related to a shorter final height in these children.

[jsv22]

i'm not sure how to post a .pdf, shoot me a pm with your email addy and i'll send it to you

-jsv

[turboturist]

i'm not sure how to post a .pdf, shoot me a pm with your email addy and i'll send it to you

-jsv

You can post it the same as a picture. When you hit "post reply", then manage attachments button and attach it.

[St]

It can't hurt to give it a shot.Read your article sound very good for the Former NFL players.

[turboturist]

i'm not sure how to post a .pdf, shoot me a pm with your email addy and i'll send it to you

-jsv

Thanks for the article jsv.