Pioglitazone and Insulin

[Blitz-Test]

Posted this on bb.com but was wondering the thoughts I would get at cbb









Okay so when I was at the gym today I was talking to one of my gym buddies in the steam room, and he was telling me what he was on yada yada, test tren and slin, and I said oh insulin how are you running that and stuff...

So he was telling me he used pioglitazone, while on slin he said it gets the most out of it, and it safe gaurds becoming insulin resistant,

He went on to say how pioglitazone increased your sensitivity to insulin so he could actually use a lower dose of slin while optimizing the results... He also went on to say once I asked about sides, he said that pioglitazone increased HDL, and lowered VDL while no effect on LDL...

Seems interesting, anyone have knowledge?

[GTZ3]

bump...

[Bowlcut]

So apparently the stuff lower blood sugar levels. OK. But call me stupid but does not having too low of blood sugar causes problems like diabetic shock?

[Blitz-Test]

So apparently the stuff lower blood sugar levels. OK. But call me stupid but does not having too low of blood sugar causes problems like diabetic shock?

.....

...

It doesnt just make the sugar disappear it works with the insulin to feed to the muscle tissue.... It would be similiar to using artificial insulin, you shoot and eat carbs like no tommorow feeding your muscles... Its not just take it and then go you gotta know what your doing

[Bowlcut]

.....

...

It doesnt just make the sugar disappear it works with the insulin to feed to the muscle tissue.... It would be similiar to using artificial insulin, you shoot and eat carbs like no tommorow feeding your muscles... Its not just take it and then go you gotta know what your doing

Does it decrease insulin sensitivity of fat cells or just make the muscle ones more sensitive only?

[Seth]

From wiki "Although not clinically significant, pioglitazone decreases the level of triglycerides and increases that of high-density lipoproteins (HDL) without changing low-density lipoproteins (LDL) and total cholesterol in patients with disorders of the lipid metabolism"

still from wiki "It modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the lipidic, muscular tissues and in the liver."


This is an uneducated analysis, but as far as I understand, raising your sensitivity to insulin while you inject insulin is an highway to hypoglycemia. Plus, gains won't be all that lean. The other side effects don't sound that bad though.