serm ingestion timing

[L3]

i'm starting pct on monday, i'm going to be running the following protocol:

week 1-3 clomid @ 100mg
week 1-3 nolva @ 20mg
week 4-6 nolva @ 40mg

week 1-6 tribulus extract @ 6g
week 1-6 Zeus @ 6 pills


my question, how should i spread out the nolva and clomid during the day?

should i try to spread dosages out to keep a stable level in my blood?
do i take it before bed?
do i take it with food?

ty !

[RagingRandy]

Absorption and Distribution

Following a single oral dose of 20 mg tamoxifen, an average peak plasma concentration of 40 ng/mL (range 35 to 45 ng/mL) occurred approximately 5 hours after dosing. The decline in plasma concentrations of tamoxifen is biphasic with a terminal elimination half-life of about 5 to 7 days. The average peak plasma concentration of N-desmethyl tamoxifen is 15 ng/mL (range 10 to 20 ng/mL). Chronic administration of 10 mg tamoxifen given twice daily for 3 months to patients results in average steady-state plasma concentrations of 120 ng/mL (range 67-183 ng/mL) for tamoxifen and 336 ng/mL (range 148-654 ng/mL) for N-desmethyl tamoxifen. The average steady-state plasma concentrations of tamoxifen and N-desmethyl tamoxifen after administration of 20 mg tamoxifen once daily for 3 months are 122 ng/mL (range 71-183 ng/mL) and 353 ng/mL (range 152-706 ng/mL), respectively. After initiation of therapy, steady state concentrations for tamoxifen are achieved in about 4 weeks and steady-state concentrations for N-desmethyl tamoxifen are achieved in about 8 weeks, suggesting a half-life of approximately 14 days for this metabolite. In a steady-state, crossover study of 10 mg NOLVADEX tablets given twice a day vs. a 20 mg NOLVADEX tablet given once daily, the 20 mg NOLVADEX tablet was bioequivalent to the 10 mg NOLVADEX tablets.


So it looks like twice a day is optimal unless you are running it longer than 4 weeks.


Clomid
If you are getting 50mg Clomid it would not hurt to split the dose. Clomid does have a very long half life.

Natural Supplements
From what I was told by a naturapath natural supplements and viamins should always be taken after you eat to aid in absorption.

Have you considered HCG?

[L3]

thanks for the info bro.

im not running HCG, i wasn't on anything overly suppresive this time. also, i was under the impression that HCG shouldn't be used for PCT, but actually throughout the cycle itself.

next cycle im def throwing that in tho its gonna be a good one :D