aas and blood sugar levels?

[Vitamin S]

hi p,

do any aas compounds lead to blood sugar problems or diabetes in long run. just curious if aas can cause ones insulin levels to go up and down?

thx

and what do you usually eat for breakfast.

[shainesboostin]

Im a type 1 diabetic, and noticed when I tried Dbol, I required WAY more insulin...

[Praetorian]

hi p,

do any aas compounds lead to blood sugar problems or diabetes in long run. just curious if aas can cause ones insulin levels to go up and down?

thx

and what do you usually eat for breakfast.

No Ive never heard or seen anything to that effect....breakfast eggs, oats etc.
P

[Vitamin S]

thanks p,

is the below quote true

Steel-cut oats have a lower glycemic index than instant oatmeal (42 vs. 66, respectively), causing a lower spike in insulin levels when consumed.[

if so i will switch over. currently i am using plain quaker instant oat packs. is a gi of 66 bad for breakfast?

currently my breakfast is a shake consisting of

1 cup egg whites
1 scoop whey isolate
75g of quick instant plain oats
dash of cinnamon
1 tbsp of extra virgin olive oil

thx

[natenator]

Instant oats are refined thus typically see higher GI but what really matters is the glycemic load of an entire meal. Fats and proteins blunt insulin response to a large degree (assuming its not pure glucose -sugar- being injested) therefore most ppl blow the gi of a particular food way out of proportion though it does help to start with the lowest gi foods as possible :)


thanks p,

is the below quote true

Steel-cut oats have a lower glycemic index than instant oatmeal (42 vs. 66, respectively), causing a lower spike in insulin levels when consumed.[

if so i will switch over. currently i am using plain quaker instant oat packs. is a gi of 66 bad for breakfast?

currently my breakfast is a shake consisting of

1 cup egg whites
1 scoop whey isolate
75g of quick instant plain oats
dash of cinnamon
1 tbsp of extra virgin olive oil

thx

[Andre Gregoire]

This is Prae's thread so I don't want to impose but I have seen a bunch of studies showing that high dosages of AAS can lead to insulin resistance. Low dosages like in HRT generally improve insulin sensitivity.

[Praetorian]

This is Prae's thread so I don't want to impose but I have seen a bunch of studies showing that high dosages of AAS can lead to insulin resistance. Low dosages like in HRT generally improve insulin sensitivity.

Post them please...id love to see the mechanism from aas inducing insulin resistance...even if this does happen the effect would most likely be insignificant...otherwise you would be seeing alot more issues with BB's and type 2 diabetes.
P

[Praetorian]

thanks p,

is the below quote true

Steel-cut oats have a lower glycemic index than instant oatmeal (42 vs. 66, respectively), causing a lower spike in insulin levels when consumed.[

if so i will switch over. currently i am using plain quaker instant oat packs. is a gi of 66 bad for breakfast?

currently my breakfast is a shake consisting of

1 cup egg whites
1 scoop whey isolate
75g of quick instant plain oats
dash of cinnamon
1 tbsp of extra virgin olive oil

thx


Less refined generally means lower GI.
P

[Andre Gregoire]

Here are a few studies that you might find interesting. I first learned about the link from a physiology textbook and since then I have seen the link between AAS and Insulin Resistance mentioned in passing in medical articles when researching Insulin Resistance and HRT.

Since I stopped using AAS over 7 years ago I really stopped researching this stuff so wasn't really current with everything. After digging into pubmed for a while I realized this is a complicated topic.

First off, in many studies the subjects are using AAS and HGH so it's hard to say which is responsible and we already know that HGH can do it. Second of all, researchers sometimes refer to HGH as AAS, so the headline of the study might say that AAS causes insulin resistance and when you read it they talk about HGH being the AAS... WTF? Also, in the subjects that self-report using AAS, they probably weren't asked if they also used HGH.

Testosterone up to 600mg per week seems to not cause any issues, 17 alpha-alkylated seem to be more linked with the problem so there is perhaps a liver element to this equation.

Combining HGH + Anadrol was worse than either alone so there appears to be a cumulative effect.

Abbas Khatami just admitted on Heavy Muscle Radio that he is now a Type 1 diabetic and said that many other pro's are too but no one wants to admit it.


------------------
(Powerlifters who ingested anabolic steroids had diminished glucose tolerance compared to the nonsteroid-using group, despite having substantially higher postglucose serum insulin concentrations.)

J Clin Endocrinol Metab. 1987 May;64(5):960-3.
Insulin resistance and diminished glucose tolerance in powerlifters ingesting anabolic steroids.
Cohen JC, Hickman R.
http://www.ncbi.nlm.nih.gov/pubmed/3549761
------------------

(Two observations from the study:
1. Pharmacological administration of anabolic steroids to both men and women increases glucose and insulin concentrations and also insulin resistance.
2.Total testosterone and SHBG have been associated with defects in nonoxidative glucose disposal and upper body adiposity in normoglycemic Finnish men.)

Horm Res. 1996;45(3-5):233-7.
Sex hormone-binding protein, hyperinsulinemia, insulin resistance and noninsulin-dependent diabetes.
Haffner SM.
SourceDepartment of Medicine, University of Texas Health Science Center at San Antonio 78284-7873 USA.
http://www.ncbi.nlm.nih.gov/pubmed/8964590

---------------------
(More recent studies indicate that glucose intolerance, insulin resistance, increased cardiovascular disease risk profiles, cerebral dangers, musculoskeletal injuries, prostate cancer, psychosis and schizophrenic episodes, among others, accompany anabolic steroid intake.)

Med Toxicol Adverse Drug Exp. 1989 Jul-Aug;4(4):254-71.
Adverse effects of anabolic steroids.
Hickson RC, Ball KL, Falduto MT.
SourceDepartment of Physical Education, University of Illinois, Chicago.
http://www.ncbi.nlm.nih.gov/pubmed/2671596
---------------------

(Not the best example as the subject was using HGH as well)

Hum Exp Toxicol. 2011 May 9. [Epub ahead of print]
New onset diabetes associated with bovine growth hormone and testosterone abuse in a young body builder.
Geraci MJ, Cole M, Davis P.
SourceBaptist Medical Center Downtown, Emergency Department, Jacksonville, FL, USA.
http://www.ncbi.nlm.nih.gov/pubmed/21558143
----------------

(Not the best example because the sujbects have Turner Syndrome but the study shows that combined treatment with HGH and Anadrol resulted in a significant increase of insulin secretion and increased insulin resistance greater than either substance alone. There is a cumulative effect on inuslin resistance to take HGH + AAS.)

Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 2005;11(2):79-84.
[Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both].
[Article in Polish] Starzyk J.
SourceKlinika Endokrynologii Dieci i Mlodziezy Katedry Pediatrii, Collegium Medicum UJ w Krakowie, Kraków. mistarzy@cyf-kr.edu.pl
http://www.ncbi.nlm.nih.gov/pubmed/15996336
----------------

(These patients[...]all demonstrated glucose intolerance following institution of androgen therapy[..]Androgen-induced glucose intolerance may play a major role in the pathogenesis of both the pancreatic and hepatic abnormalities.)

Arch Pathol Lab Med. 1979 Aug;103(9):483-5.
Hypertrophy and hyperplasia of islets of Langerhans associated with androgen therapy.
Novak R, Wilimas J, Johnson W.
http://www.ncbi.nlm.nih.gov/pubmed/380511
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