Tank
30-04-2008, 12:05 PM
Got this from Dr.Will Brink
This review of 72 studies puts to rest unfounded fears some may have that there is any risk of testosterone replacement therapy – which brings men from a low testosterone state to a ‘healthy normal’ state - at least where it concerns CVD or prostate cancer. As the game show host would say, but wait, there’s more!
A recent study published online November 26, 2007 in the journal Circulation, found there was an inverse risk for men with low testosterone and all cause mortality. Translated, men with the lowest levels of testosterone had the highest mortality rates from all causes including heart disease and cancer! The authors of this study commented
“…these findings are consistent with existing evidence from epidemiological and clinical studies indicating that endogenous testosterone concentrations may be an indicator of good health."
men given supraphysiological doses (meaning much higher than normal) of this hormone don’t generally find serious side effects. For example, a study published in The New England Journal of Medicine (NEJM) - considered one of the most prestigious medical and scientific journals in the world – found healthy men given 600mg per week (about 6 times higher than the typical replacement dose) of testosterone did not suffer any serious side effects, negative changes in lipid profiles, and did not see a rise in prostate-specific antigens, or increased aggression. •••
But what if the person has already had a heart attack? Interestingly, one study suggests testosterone therapy may actually help after a heart attack, but it’s preliminary research done on animals. ••••
So what about the very high doses of testosterone and other anabolic steroids used by high level bodybuilders and other athletes mentioned above? As with pretty much any hormone, below a certain levels, health issues arise and above a certain level, the same thing happens, though the health issues may or may not be the same. For example, very high levels or very low levels may present an increased risk for cardiovascular disease (CVD) but far more is known about too little vs. too much when it comes to testosterone and CVD or prostate issues, etc. At the very high doses used by some athletes it would not surprise me if there was an increased risk of CVD
This review of 72 studies puts to rest unfounded fears some may have that there is any risk of testosterone replacement therapy – which brings men from a low testosterone state to a ‘healthy normal’ state - at least where it concerns CVD or prostate cancer. As the game show host would say, but wait, there’s more!
A recent study published online November 26, 2007 in the journal Circulation, found there was an inverse risk for men with low testosterone and all cause mortality. Translated, men with the lowest levels of testosterone had the highest mortality rates from all causes including heart disease and cancer! The authors of this study commented
“…these findings are consistent with existing evidence from epidemiological and clinical studies indicating that endogenous testosterone concentrations may be an indicator of good health."
men given supraphysiological doses (meaning much higher than normal) of this hormone don’t generally find serious side effects. For example, a study published in The New England Journal of Medicine (NEJM) - considered one of the most prestigious medical and scientific journals in the world – found healthy men given 600mg per week (about 6 times higher than the typical replacement dose) of testosterone did not suffer any serious side effects, negative changes in lipid profiles, and did not see a rise in prostate-specific antigens, or increased aggression. •••
But what if the person has already had a heart attack? Interestingly, one study suggests testosterone therapy may actually help after a heart attack, but it’s preliminary research done on animals. ••••
So what about the very high doses of testosterone and other anabolic steroids used by high level bodybuilders and other athletes mentioned above? As with pretty much any hormone, below a certain levels, health issues arise and above a certain level, the same thing happens, though the health issues may or may not be the same. For example, very high levels or very low levels may present an increased risk for cardiovascular disease (CVD) but far more is known about too little vs. too much when it comes to testosterone and CVD or prostate issues, etc. At the very high doses used by some athletes it would not surprise me if there was an increased risk of CVD