Tren cough

[Turtle]

what is up with that? I have had a few light coughs from tren but today i almost puked it was so bad. Kinda scared me. Maybe tren isn't good for you lol.

[Mr Ontario]

Stop injecting it into your abs....I have told you over and over again! :)


what is up with that? I have had a few light coughs from tren but today i almost puked it was so bad. Kinda scared me. Maybe tren isn't good for you lol.

[shithead]

In your shoulders? seems it happens to me more from medial delt shots. Acetate more than enanthate.

[shithead]

Tren- Fat burning and "fina cough" both from prostaglandin metabolization

Posted on AR & IBB as well-


It's been widely disussed of Trens fat burning properties through rises in IGF and Prostaglandins. While IGF is a fairly well known substance in the bodybuilding world today, prostaglandins are fairly unknown in terms of formation and roles in the body.
So below, a brief dicription of prostoglandins and their role in fat burning, "fina cough", and why a person going through Tren administration can experience it's fat burning effects without the dreaded "Cough"

The term prostaglandin comes from the word-Prostate. The first prostoglandins were first dicovered in semen about the mid 1930's and it was thought that prostaglandins were made from the prostate. Since this time, it has been dicovered that most prostaglandins are not even constructed in the prostate.

Prostaglandins are made by two different pathways(Cyclooxygenase and Lipoxygenase), and considering prostaglandins are a group of about 20 lipid cells, they have contrary function; responsible for stimulating as well as alleviating inflammation(Inflammation stimulation is the rapid metabolism of them expelled through the bronchials), regulate blood flow to particular organs, control ion transport across membranes, modulate synaptic transmission, induce sleep, mediate lipid release, and regulate metabolism is various tissue.

Prostaglandins are synthesized from arachidonate(Lipoxygenase which catalyze the dioxygenation of polyunsaturated fatty acids) in the cell membrane by the action of phospholipase A2. Cyclooxygenase and lipoxygenase pathways, compete with one another to form prostaglandins(as well as thromboxane or leukotriene-leukotriene being a bronchial stimulator),
In the cyclooxygenase pathway, the prostaglandins D, E and F plus thromboxane and prostacyclin are made. Thromboxanes are made in platelets and cause constriction of vascular smooth muscle and platelet aggregation
Leukotrienes are made in leukocytes and macrophages via the lipoxygenase pathway. They are potent constrictors of the bronchial airways. They are also important in inflammation and hypersensitivity reactions as they increase vascular permeability.

Being that prostaglandins from either pathway, are still fatty acids of a group, they mediate lipid release and controll tissue metabolization, so fat burning is a luxerry of either pathway of formation. It's the pathway from which they are constructed that dictates "fina cough". As prostaglandins made from the Cyclooxygenase pathway dictate muscle constriction and platlet aggregation, and the Lipoxygenase pathway dictates bronchial constriction(the main form of expulsion)


Refs:
Cackatoo Press
Columbia Encyclopedia 6th Edition
Science Daily Magazine

[Mr Ontario]

Ya...but ShitHead can you sum that up in English? :)


Tren- Fat burning and "fina cough" both from prostaglandin metabolization

Posted on AR & IBB as well-


It's been widely disussed of Trens fat burning properties through rises in IGF and Prostaglandins. While IGF is a fairly well known substance in the bodybuilding world today, prostaglandins are fairly unknown in terms of formation and roles in the body.
So below, a brief dicription of prostoglandins and their role in fat burning, "fina cough", and why a person going through Tren administration can experience it's fat burning effects without the dreaded "Cough"

The term prostaglandin comes from the word-Prostate. The first prostoglandins were first dicovered in semen about the mid 1930's and it was thought that prostaglandins were made from the prostate. Since this time, it has been dicovered that most prostaglandins are not even constructed in the prostate.

Prostaglandins are made by two different pathways(Cyclooxygenase and Lipoxygenase), and considering prostaglandins are a group of about 20 lipid cells, they have contrary function; responsible for stimulating as well as alleviating inflammation(Inflammation stimulation is the rapid metabolism of them expelled through the bronchials), regulate blood flow to particular organs, control ion transport across membranes, modulate synaptic transmission, induce sleep, mediate lipid release, and regulate metabolism is various tissue.

Prostaglandins are synthesized from arachidonate(Lipoxygenase which catalyze the dioxygenation of polyunsaturated fatty acids) in the cell membrane by the action of phospholipase A2. Cyclooxygenase and lipoxygenase pathways, compete with one another to form prostaglandins(as well as thromboxane or leukotriene-leukotriene being a bronchial stimulator),
In the cyclooxygenase pathway, the prostaglandins D, E and F plus thromboxane and prostacyclin are made. Thromboxanes are made in platelets and cause constriction of vascular smooth muscle and platelet aggregation
Leukotrienes are made in leukocytes and macrophages via the lipoxygenase pathway. They are potent constrictors of the bronchial airways. They are also important in inflammation and hypersensitivity reactions as they increase vascular permeability.

Being that prostaglandins from either pathway, are still fatty acids of a group, they mediate lipid release and controll tissue metabolization, so fat burning is a luxerry of either pathway of formation. It's the pathway from which they are constructed that dictates "fina cough". As prostaglandins made from the Cyclooxygenase pathway dictate muscle constriction and platlet aggregation, and the Lipoxygenase pathway dictates bronchial constriction(the main form of expulsion)


Refs:
Cackatoo Press
Columbia Encyclopedia 6th Edition
Science Daily Magazine

[Turtle]

Ya...but ShitHead can you sum that up in English? :)

was thinking the same thing lol.

was a shot to the quad

[brad_2626]

I've started using Tren E, 150 e3d. While I don't get the "cough", my body temperature seems to fluctuate all day long. I have both hot and cold sweats all day long, not just at night. And this all started to happen within hours of the shot.

[shithead]

The prostaglandins that the tren creates cause an inflamatory effect esp. for the brochial airways. This is why aerobic capacity is hindered with this drug as well.

[Mr Ontario]

So your saying I shouldn't attempt to swim across the lake this summer as I may drown? Cough and then get a gulp of water in my mouth at the same time gas out.


The prostaglandins that the tren creates cause an inflamatory effect esp. for the brochial airways. This is why aerobic capacity is hindered with this drug as well.

[shithead]

I dont know if this would transfer to us, but kinda cool.

Abstract Trenbolone (TBOH), a synthetic androgen used as an anabolic agent in livestock, has been tested for mutagenicity in the Salmonella assay, for covalent DNA-binding in vitro, for induction of unscheduled DNA synthesis in HeLa cells and Syrian hamster embryo (SHE) fibroblasts and for morphological transformation of SHE cells. While TBOH gave negative results in the assays for mutagenicity and DNA damage, it was clearly capable of transforming SHE cells in culture. The natural androgen testosterone did not transform these cells. Thus, TBOH appears to be a substance which can transform cells independent of its hormonal action and without grossly damaging DNA.

D. Schiffmann1 Contact Information, M. Metzler1, T. Neudecker1 and D. Henschler1
(1) Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Str. 9, D-8700 Würzburg, Federal Republic of Germany

[shithead]

So your saying I shouldn't attempt to swim across the lake this summer as I may drown? Cough and then get a gulp of water in my mouth at the same time gas out.

lol that would be a horrible death.

[IronRobi]

I've been lucky and only had the tren cough once. It was from a quad shot as well. I was coughing so hard I was expecting my lungs to flop out onto the floor. I've heard from those who get it often that they seem to be more affected the closer the shot is to the lungs (ie delts) but this could easilly be all in their head and there is no scientific proof behind that.

[shithead]

The enanthate doesnt spike levels as fast as the acetate so tren "cough" is less of a factor.

[bigdaddydrew123]

ive gotten cough from test e before, was explained to me i hit a vein, with tren i get a burning sensation sometimes in my lungs

[Rrrrolla]

I read a while ago that tren acetate irritates the fibers in your lungs, and the only way it can get there really quickly is if you nick or inject directly into a vein. It SUCKS! I get it about 1 in 5 shots as long as they are over a ml.

[Mr Ontario]

Especially if the do an autopsy and find out the real reason I drowned! :)


lol that would be a horrible death.

[Turtle]

well two for two now. maybe its quad shots as those are last resort injection sites for me. could be more blood vessels to break and tren to get in. the rest of my injection sites are all scar tissue lol so maybe that protects.

[shithead]

well two for two now. maybe its quad shots as those are last resort injection sites for me. could be more blood vessels to break and tren to get in. the rest of my injection sites are all scar tissue lol so maybe that protects.

Acetate or enanthate?

[Mr Ontario]

May be time to retire!? :)


well two for two now. maybe its quad shots as those are last resort injection sites for me. could be more blood vessels to break and tren to get in. the rest of my injection sites are all scar tissue lol so maybe that protects.

[shithead]

The second shot that I ever did was a quad shot, couldnt walk for a week. Since then I havent tried another.

I have crazy scar tissue as well, at first it was my glutes so I switched to delts, now my delts are like plywood too.

I am training without juice now and its a tough road. It was a lot easier before I cycled.

[bigdaddydrew123]

well two for two now. maybe its quad shots as those are last resort injection sites for me. could be more blood vessels to break and tren to get in. the rest of my injection sites are all scar tissue lol so maybe that protects.i hated quad shots at first but now their my favorite, just gotta get used to it. tris are supposed to be good too

[Rrrrolla]

i hated quad shots at first but now their my favorite, just gotta get used to it. tris are supposed to be good too


I bet tris are great, now how the heck are you suppoed to get a pin back there? Try it tonight bro, let me know how that works out for ya... :)

[IronRobi]

I bet tris are great, now how the heck are you suppoed to get a pin back there? Try it tonight bro, let me know how that works out for ya... :)

I've done tri's once... ended up with a huge bruise the size of a baseball on the back of my arm. Go for calves, my absolute fav!

[bigdaddydrew123]

I bet tris are great, now how the heck are you suppoed to get a pin back there? Try it tonight bro, let me know how that works out for ya... :)
new favorite spot triceps, hold arm straight in front underhand it. even muscle bound geeks can do it!

[Mr Ontario]

Ya...your nut's...You must have a pretty big tri's to being doing that!? What are you putting in there...that doesn't take you 3-4 days for it to heal/not be sore?


new favorite spot triceps, hold arm straight in front underhand it. even muscle bound geeks can do it!

[IronRobi]

new favorite spot triceps, hold arm straight in front underhand it. even muscle bound geeks can do it!

Let us know how big of a bruise you get after :p

[Houstonbc]

man i do tris all the time! its a bigger muscle than bi's i dont bruise but ive just been using cyp and eq 1ml per shot. its simple check out spotinjections.com next to delts its the least painful spot for me

[shithead]

triceps is three muscles, hence the name.

[bigdaddydrew123]

Let us know how big of a bruise you get after :pya its t 400 too ill let you know , wuss:laugh:laugh

[Turtle]

im using acetate. delt shot no problems.

[Musclehead]

I read in muscular development that it MAY be due to delt injections..and breathing in the aroma. Dave Palumbo said that it rarely happens anywhere else, just delts and that's all the explanation he could come up with....not sure if that makes sense.

[bigdaddydrew123]

Ya...your nut's...You must have a pretty big tri's to being doing that!? What are you putting in there...that doesn't take you 3-4 days for it to heal/not be sore?cmon mr o your inner head of your tri must have as much meat as your side delts. its now day after and tris are fine, i highly recommend.

[Mr Ontario]

Ya...they are but....I need them not to be sore unless I actually worked them out hard. If they feel sore/stiff/ache for three days then I still need to do back/shoulders/chest etc. + The last thing I need is to get an infection in that area...not worth it to me. When I can shoot ......Quads/ass/bicept's/chest/shoulders...thats 10 shots. No need to add tris a hard to reach/plunge oil into area.


cmon mr o your inner head of your tri must have as much meat as your side delts. its now day after and tris are fine, i highly recommend.

[Mr Ontario]

P.S I have seen to may guy's with infections in that area. Down to there elbow/across to there bicep...where they said they never do it again. Lesson learned. lol

[bigdaddydrew123]

P.S I have seen to may guy's with infections in that area. Down to there elbow/across to there bicep...where they said they never do it again. Lesson learned. lol
ya infections are nasty anywhere, i need new areas glutes are out for awhile. when wife goes for allergy shots they do tris every time. ill let you guys know if theres any probs, for now i have delts quads tris. ive done chest with tren, done bis and front delts.if your doin eod you gotta get creative. biceps were the worst so far

[IronRobi]

ya its t 400 too ill let you know , wuss:laugh:laugh

Wuss?? Damnit drew! Now I'm going to have to try tri's again. hahaha

[bigdaddydrew123]

Wuss?? Damnit drew! Now I'm going to have to try tri's again. hahaha
its not that bad. tris feel like i trained them yesterday, keep volume small i did 1 cc in each,work your way up. to me its a good spot muscle gets lots of activity.id rather have sore tris than sore ass.