clomid as an Anti-E

[Turtle]

would clomid do anything if you are maybe getting slight itchy nipples and only have it around? How much do you suggest using? or a complete waste of time?

[St]

I take 100mg ed.

[MAJIN VEGETA]

100mg ed, I personaly respond to clomid very well and have never had issues of it making a itchy nipple problem worse. You could also go lower on the dose just take it for a longer time, Clomid has never stopped me from gaining weight while other products remove to much estrogen and as such some gains.

MAJIN VEGETA

[Mr.Freeze]

Gyno from what?

[thelittleguy]

get yourself some nolva

[outshine]

i find that using a little bit of clomid helps when my estorgen levels are just a little bit too high (like in your case). If 100mg of clomid doesn't do the trick take something stronger. I'm using a combination of clomid and arimidex for estrogen control while on test/tren. My justification is that tren is largely so effective because of its positive impact on igf-1 and nolva, i've read, has a negative impact on igf-1 production.Hence, i don't want to lower my levels unless it is absolutely necessary. Also, i find using a bit of clomid while on cycle helps keep the boys from getting too small. In cases where the nips are getting too sensitive or itchy ill pop some nolva but usually the clomid and adex works.

I do agree that nolva is superior in terms of estrogen blocking but i save it for pct and when i actually need it.

[Turtle]

yeah i have nolva on the way but will take some time... gyno from test. been thinking maybe if could be tofu too lol. i have been eating alot of "healthy" baked goods as i feel better about it if they are remotely good for you. They use alot of tofu. I have never eaten tofu before but know it's a fairly powerful estrogen. Maybe combo of test and tofu is making my gyno prone lol. Time to drop the muffins.

Thanks for the input.. will try some clomid see how it goes.

[Musclehead]

I've heard it could make it worse, not sure if that's true. I'd get some arimidex or Nolva asap. Somebody mentioned to me that 6 oxo might be good for gyno....it's a legal sup...not sure if that is possible though.

[Turtle]

I've heard it could make it worse, not sure if that's true. I'd get some arimidex or Nolva asap. Somebody mentioned to me that 6 oxo might be good for gyno....it's a legal sup...not sure if that is possible though.


shit lol.. dont want it worse... i think i heard the that nolva too can have adverse reactions in some. hope thats not the case with me.

my nolva should be here in a week or so.. guessi could lower my dose of test. but thats no fun lol

[MAJIN VEGETA]

I had used Nolva after most of my cycles to recover but as I have stated in another thread Nolva kills my immune system, it shuts my body down hard and fast, makes me sick, Notice I say me, and my body, I can see how Nolva works for some but I am just saying Clomid has never had that effect on my body, and I don’t get emotional from the clomid like others do, but that could just be because I don’t use high doses, I would much rather take it longer and at a smaller dose. Everyone's Body chemistry is different and NO we are not all created equally So what works for some may not work for others, Never mind how Clomid works in the body, I am sure it works slightly different in everybody, Side effects of taking any drug some get them some don’t. Also as far as Nolva goes, Toremifene Citrate works better than them all. By the looks of Turtles pics, he looks like to me anyways that it might be more of a progesterone issue; Serums that work fast in my opinion are Cabergoline, Letrozole, and Clomid/Toremifene Citrate. The reason I would think Turtles condition is more progesterone is he looks like he uses enough dht/low estrogen products to combat estrogen, but if he’s a fan of Tren, and other derivatives’ it might be worthwhile to get some Cabergoline.

MAJIN VEGETA

[thelittleguy]

nolva is not the greatest for the system, and is actually carcinogenic. but... in this case its the best remedy for the situation. chlomid is useless in this situation...its used to trigger the production of test after cycle,

[MAJIN VEGETA]

by Bill Roberts - Clomid is the anti-estrogen of choice for improving recovery of natural testosterone production after a cycle, improving testosterone production of endurance athletes, and is also effective in reducing risk of gynecomastia during a cycle employing aromatizable steroids.

While it has been claimed that Clomid "stimulates" production of LH and therefore of testosterone, in fact Clomid’s activity is achieved not by stimulation of the hypothalamus and pituitary, but by blocking their inhibition by estrogen.

Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist -- the cofactor used in that tissue cannot bind and so the receptor remains inactive -- and in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind.

Clomid is an effective antagonist in the hypothalamus and in breast tissue. It is an effective agonist in bone tissue, and for improving blood cholesterol.

Clomid also has the property of reducing the adverse effect of exercise-induced damage of muscle tissue. This is very significant for endurance athletes but is not very significant, if at all significant, with reasonable weight training. Clomid does not perceptibly affect gains of the weight trainer either favorably or adversely in my experience.

The drug seems to have estrogenic effects on mood, which can be beneficial (improving relationships with women by improving empathy) or can yield depression or PMS-like symptoms, but for most users there is no significant effect either way.

The claim that duration of intake should not exceed 10-14 days is incorrect. Clinical studies with male patients have been for periods of a year or longer. This error probably originates from the fact that, for use in women, due to the menstrual cycle there would obviously be no point in trying to stimulate ovulation all four weeks of the month. Thus, use in women is limited to 10-14 days. That limitation is not because of toxicity.

Clomid is in fact useful throughout a cycle if aromatizable drugs are being used. I do think however that to be conservative, one should use it no more than 2/3 of the time throughout the year or a little less.


MAJIN VEGETA

[thelittleguy]

good to know.

[St]

Very well said Majin.It does two things for the price of one.

[Turtle]

thanks for info. Current cycle is EQ, Test and yeah a bit of tren. Test dose may be a bit higher then i usually go. I guess it could be the tren but i think the tren is fake lol. So doubt it, but guess i could be wrong.

[Turtle]

some intersting info here:

Grapefruit link to breast cancer

Eating too much grapefruit could increase risks of breast cancer
Eating grapefruit every day could raise the risk of developing breast cancer by almost a third, US scientists say.
A study of 50,000 post-menopausal women found eating just a quarter of a grapefruit daily raised the risk by up to 30%.

The fruit is thought to boost levels of oestrogen - the hormone associated with a higher risk of the disease, the British Journal of Cancer reported.

But the researchers and other experts said more research was still needed.

This is an interesting study, but is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health

Dr Joanne Lunn

The women had to fill in questionnaires saying how often they ate grapefruit and how big their portions were.

Oestrogen important

The researchers, at the universities of Southern California and Hawaii, found that women who ate one quarter of a grapefruit or more every day had a higher risk of breast cancer than those who did not eat the fruit at all.

Previous studies have shown that a molecule called cytochrome P450 3A4 (CYP3A4) is involved in metabolising oestrogen hormones.

And grapefruit may boost blood oestrogen levels by inhibiting this molecule, allowing the hormones to build up.

The researchers found that in women who ate at least a quarter of a grapefruit daily, levels of oestrogen were higher.

They said: "It is well established that oestrogen is associated with breast cancer risk.

"Therefore, if grapefruit intake affects oestrogen metabolism leading to higher circulating levels, then it is biologically plausible that regular intake of grapefruit would increase a woman's risk of breast cancer."

More research

And they said this was the first time a commonly eaten food had been linked to an increased risk of breast cancer in older women.

However, they warned that more research was needed to confirm the findings which may have been affected because they only took into account intake of the fruit, but not grapefruit juice.

Breast cancer accounts for almost a third of all cancers in women, and previous lifestyle factors linked to the disease include drinking alcohol and being overweight.

Dr Joanne Lunn, a nutrition scientist at the British Nutrition Foundation said: "This is an interesting study of a large group of post-menopausal women whose diet and health have been followed for many years.

"However, this study is simply a piece of the jigsaw that will eventually help us to understand how our diets affect our health.

"Although we are beginning to get a better awareness of how our diets can modify the risk of diseases such as cancer, we are still a long way from identifying particular foods that might specifically increase or decrease risk."

However, she said that some dietary patterns are associated with a reduced risk of certain cancers and that a diet rich in a variety of different fruits and vegetables could help reduce the risk of heart disease and some cancers

[Turtle]

to sum that up, the enzyme that grapefruits block is responsible for breaking down estrogen. I eat a grapefruit a day. So maybe a grapfruit a day, too much tofu cookies o and a gram of test per week has put me over the edge lol.


Picked up some 6-oxo today from GNC.. Will see how that works until other stuff gets here.

[lambchops]

so im in my third week of 500 test e/week. my nipples are getting increasingly sensitive, no hard bumps no itch, acne has also increased but im only concerned with the nipple issue.

i got clomid and tamoxiplex on hand, any suggestions?

[bossman_1986]

actually guys clomid is not an anti estrogen, its a SERM (selective estrogen receptor modulator) just like nolvadex

arimidex, aromasin are anti estrogens

[St]

so im in my third week of 500 test e/week. my nipples are getting increasingly sensitive, no hard bumps no itch, acne has also increased but im only concerned with the nipple issue.

i got clomid and tamoxiplex on hand, any suggestions?


.

[BAM]

With regard to your clomid question:





In addition to helping with the post-cycle testosterone crash, this drug can also help with elevated estrogen levels during a steroid cycle. A high estrogen bevel puts an athlete in serious risk of developing gynecomastia, which is an obvious unwanted side effect. With the intake of Clomid, the athlete can hopefully reduce his risk for developing gynecomastia. The estrogen "blocking" properties of Clomid appear to be slightly weaker than Nolvadex in comparison however, which is why it is not usually thought of as an equal substitute for estrogen maintenance. Of course both drugs have similar actions in the body. and are relatively interchangeable for this purpose. Clomid can likewise also be used as a maintenance anti-estrogen throughout the duration of steroid cycle with good confidence, just as is done with Nolvadex. In most instances this will prove equally sufficient, the drug effectively minimizing the activity of estrogen in the body and warding off gyno and excess water/fat retention. Unfortunately just as with Nolvadex this is not always the case however, and many find it necessary to addition another anti-estrogenic drug. The most common adjunct is Proviron, an oral DHT used to competitively lower aromatase activity and raise the androgen to estrogen ratio. The Clomid/Nolvadex and Proviron combination is extremely effective, although we could alternately replace them both with a more specific aromatase inhibitor such as Arimidex,Femara, or Aromasin. While stronger at combating estrogen in most cases, these drugs are also typically much more costly.

[St]

so im in my third week of 500 test e/week. my nipples are getting increasingly sensitive, no hard bumps no itch, acne has also increased but im only concerned with the nipple issue.

i got clomid and tamoxiplex on hand, any suggestions?


Ya take your nolva's at 20-40mg ed.