Peptide- GW 1516 dosage help

[theguy333]

Can anyone help me on the dosage for this particular peptide?(GW 1516) I've heard that it is 2-5 mg per kilogram of body weight. ED or EOD or Three times a week. Haven't found any stable sources to begin my experiment. Would it be different for a male or female subject?
This is not a commonly used peptide and is new. It is similar to Aicar. I can find dosing for that but then again it is not Aicar I am using in my research. Please Any help?

[cog]

For all the rest of us still in the dark.

http://en.wikipedia.org/wiki/GW_501516

[jshort]

Although that peptide enhances the endurance in mice, I recall reading somewhere that its probably useless for human use.

While GW 1516 is pretty much available nowhere, I've seen aicer being sold on some research drug sites.

[theguy333]

I have a bottle of GW 1516 and can locate it pretty well and not Aicar, although I have not tried very hard, the company I got the GW from does not sell Aicar.
The research I have done shows that it (GW1516) will produce similar results in humans. The research studies I have read were done on rats and obese men. GW 1516 showing a significant decrease in fat loss with little to no training. And it showed an increase in endurance only when coupled with training.
Aicar however produces fat loss and increases endurance without training.

This is why these two compounds are being called "Exercise in a pill"

Here is a webisite that has some pretty extensive research for those interested. http://www.rifters.com/real/articles/Narkar_et_al_Exercise_Mimetics_Cell_2008.pdf

The answer to my question earlier is 2-5 mg/kg body-weight ED. But I do advice doing your own research before solely trusting mine.

[jshort]

In your link on pg 9, they gave the mice 5mg/kg/day of GW1516 for four weeks, so perhaps you should attempt the same (or a little lower to be safe).

Is the obese human study your referring to this one: http://www.ncbi.nlm.nih.gov/pubmed/18024853

I didn't see a dosage given in the abstract unfortunately.

As far as I know, GW1516 for endurance has never been tested in humans (I assume that is why you are researching it). You cannot assume it will work the same in humans as it does in mice (otherwise products like resveratrol would be making a killing right now).

Where the heck did you buy your product?

Remember that even with the mice on GW1516, the improvements were ONLY seen when it was combined with aerobic exercise, so even if the drug "works", don't expect your research subjects to feel any more athletic by just lazing around the couch.

[theguy333]

Actually I am using it in fatloss research more than endurance. It's properties that mimic exercise intrigued me and so I thought I'd do some hands on research. If the peptide turns out to fail in the area of fatloss, I won't bother to purchase it again. However enticing endurance might be to some people it's not very to me. When only 1 hour of getting in and out of the gym is the common routine. I have no need for endurance.
In short the research will be done on a subject that carries alot of midsection weight from birthing. And this subject only exercise 1 or 2 times a week. So Fatloss is the main objective.
I plan on updating after research is done to inform the uninformed world of this very unknown and unused peptide.
I do know how ever that it must hold some value if they the authorities at the 2008 Bejing Olympics went to great lengths to find a way to test for it.

[theguy333]

jshort- to answer your question about where? PM me if interested. I highly recommend the source because they are a legit company that plays by the rules and produce fine products and are constantly having Sales that would make Mexico cry. If your into peptides.

[theguy333]

Just reading that abstract over again and yes that is where I saw it tested in humans and got my assurance for the possible "grand" affects it would have on fatloss. They said "The PPARdelta agonist (10 mg o.d. GW501516), a comparator PPARalpha agonist (20 mug o.d. GW590735), and placebo were given in a double-blind, randomized, three-parallel group, 2-week study"
But this dosage, 10mg OD, 'once daily', seems incredibly low. But maybe that's all they needed to see some results. Bc as stated before it seems 2-5mg/kg bodyweight seems to be the norm.
The good thing about this absract is that it does show that GW1516 is usable for fatloss. But the negative thing is we know nothing about the rest of the research, the subjects, etc. But like that Myo-statin inhibitor supplement and Myo-029 peptide, most reviews have debunked the hype. So we will have to wait and see if GW1516 is usable or just trash. And my 100$ will be on the teeter toter.

[jshort]

I suspect the norm or optimal dose simply isn't known. Perhaps the researchers simply guessed at using 10mg.

On the other hand, a 10 mg/day dose will certainly last you much longer than 2-5 mg/kg/day dose.

[Ritch]

I`d be willing to bet it would stack great with some of that miracle growth stuff. Ok, sorry, no more jokes about that stuff...

[theguy333]

I realize it could be crap but also realize it could work. So I'd stack it with a 5g of maybe and 10g of the next big thing.

[jshort]

Well let us know if you achieve any amazing results!

Btw, what gave you the idea to use GW1516 for fat loss over more common fat loss drugs? Have you already tried stuff like ECA, Clen, T3 or (god forbid) DNP?

[theguy333]

The lack of side effects shown in the studies I guess. And mroe so it's general properties that produce chemical exchanges that happen right after exercise to burn fat, but without having done any exercise. Other fat burning agents and yes this one too more than likely would necessitate a good training regime but possible since it produces those chemical exchanges without the exercise, maybe less exercise would be called for to burn the same amount of fat. And my subject does not exercise often so it seemed like a good one to try out. And I haven't tried any of those other ones. I'm new to the peptide game. Was thinking about Clen but then heard it can cause heart enlargement and that scared me away and a few of the guys I know that have used it say don't unless you desperate like pre contest or something. You suggest any that you know work?

[jshort]

In terms of risk free supps, I would recommend the following:

-Glucommanan (pill form only) with a large glass of water a couple times a day (preferably before meals).

- Calcium Pyruvate (6 grams or more daily).

-Caffeine and Green Tea.

Now if your one of those that loves thermogenics, then the best verified (ie scientifically reviewed) product would likely go to a product by iSatori called Lean System 7.

The most POPULAR thermogenic though would likely be one from UPS Labs call OxyElitePro.

(Note the above product isn't necessarily safe unless you have a strong tolerance for stimulants).

.................................................. ..

If your not concerned about side effects (or death!), then by far the best drug I have ever read of for weight loss is 2,4-Dinitrophenol. This drug has some nasty sides, including a couple of life threatening ones.

If your only looking for part time results (meaning you will certainly put the weight back on again), then a Clen/T3 combo (or either one by themselves) is very effective .

For slightly less efficiency (but again less sides), you could try an ECA stack, which is probably the most popular method for bodybuilders and perhaps your best choice for long term results.

HGH has been shown useful for fatloss as well, though is really expensive. You might be interested in reading a thread above this one on CJC-1295.

[theguy333]

Yea me and my wife have been on a stack of cjc-1295 and ghrp-6 for a while now and are noticing great results, including weight loss, skin tighting and smoothing and general energy levels. Probably going to do a 6 month cycle. I heard that about the general length of time to really get the best results from the GH increasing peptides such as these. The GW is just some added boost to the weight loss being undertaken by the GH increase. She's at 200mcg of both a day and I'm at 400 of ghrp-6 a day and 200 of cjc a day and am gaining weight while losing bf, its great.

[tony_canuck]

what length of time would you run the GW for?