Clen

[david18]

Hello all, I would like to know anything that anyone knows about clenbuteral or "clen"

[gicantor]

Pharmaceutical Name: clenbuterol
Effective dose: 40-160 mcg / day orally


Clenbuterol is a very widely used drug and has quite a reputation. A good one among athletes and recreational users, and a very bad one among those people who know very little about illegal performance enhancing aids. Its not a steroid. In fact, the only medical use for which clenbuterol is generally prescribed (and now being less and less prescribed thanks to its illegitimate use) is for obstructions of the air-way. People with chronic breathing disorders like asthma use this as a bronchodilator to make breathing easier. But its only one of the many things that can be achieved with the use of clenbuterol.

In terms of action this drug is best likened to the now also illegal ephedrine and its legal replacement, ma huang. All of them operate mainly by increasing the manufacture and secretion of catabolic hormones known as cathecholamines (like dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline)) which are secreted from the adrenal region. Now these hormones have a wide variety of functions. First of all they seem to alter the contractile characteristics of smooth muscle, but very specifically. Some will apparently be stimulated, and others inhibited. Amongst those inhibited, the smooth muscles in the bronchial tree, which explains its soothing effect in patients with breathing problems. What it also does is increase thermogenisis. This usually encompasses a rise in blood pressure, a stimulatory effect of the heart muscle and a resulting rise in body temperature.

Along with the reversing of the effects of insulin (and inhibiting the action of insulin) which results in a release of glycogen back into the blood stream as glucose and an inability to store or use more glycogen, it will increase the rate of protein and fat being burned in the body. For bodybuilders that appears to be the primary use of the drug. This thermogenisis and an increase in the rate of fat being burned usually has as a result that the metabolic rate of the subject its much higher and he burns more calories. This in turn results in loss of adipose tissue (the shedding of fat in other words) revealing a leaner physique with cuts and striations. The downside to this effect is that there is a concomitant rise in the rate of protein being burned. Where fat is robbed from the fatty tissue in the body, protein is generally robbed from the muscle. As with all catabolic hormones, in time muscle loss can and will occur. Which is why many opt to use this compound during a cycle of anabolic steroids that will help preserve the lean body mass while reducing the fat.

Among the other actions that cathecholamines have is an increase in aerobic capacity (facilitated by the easier breathing), a stimulation of the nervous system (facilitated by norepinephrine and acetylcholine release) and thus the skeletal muscle system, an increase in oxygen transportation (facilitated by the increased blood pressure) and an increase in vigil. These characteristics in turn combine to make this drug particularly interesting for athletes doing endurance sports and needing a boost. Especially in middle-long running numbers, this drug is widely abused and its no secret that in cycling circles clenbuterol in liquid form is combined with a painkiller and the drug EPO (synthetic erythropoeitin, a renal hormone) which increases the manufacture of red blood cells. It is then injected along the road, thereby avoiding positive tests prior to the race. Needless to say such a cocktail is very hazardous to the cardiovascular system. Just to demonstrate the wide use of this drug and its immense popularity among athletes, observe the US Olympic team. Exercise-induced asthma is an afflmiction that generally occurs in 3-7% of the population, and is in some rare cases treated with clenbuterol. In 2000 60% of US Olympic athletes claimed to have exercise-induced asthma and ALL of them were prescribed clenbuterol for this condition. An otherwise illegal drug, tolerated solely for this reason. And this while the Romanian gymnast Andrea Raducan was stripped of her gold medal for the 25 µg of norephedrine in her cold medicin she was taking...

In several animal studies1,2,3 Clenbuterol was also shown to act as an anabolic, believed to be able to impart muscle gains. This was never demonstrated in humans4 however, and there is more evidence that its effect on catabolic hormones invokes the opposite. In any case, the animal studies used much higher doses5 then one would safely recommend for humans. The late Dan Duchaine, by many held in high regard as a steroid guru and a former writer of the now defunct MM2K, believed it had something to do with the stimulation of a third beta receptor, which was different in humans as opposed to other mammals, and that this was the reason humans did not receive any anabolic benefits. As with most of what Dan said, this is very questionable, but one of many possible explanations in a debate that still rages on. Despite the many claims of other bodybuilders that still swear it has some form of anabolic action, I must say I've seen enough proof to the contrary to strongly advise against buying clenbuterol for promoting muscle mass. You may be more than sorely disappointed. Next time you see a 230 pound, 6 foot top-level cyclist, let me know and I may change my mind.

Clenbuterol, when used for its fat-burning properties is best used in a pyramid scheme. Slowly building up the dose may be more important that tapering off of it, as most first time users will rarely if ever know how they will react. Because of the effects on blood pressure its best to start with 20-40 µg per day and slowly work your way up increasing the dose every 3 days by 20 µg, to a maximum of 120-160 µg (most find 80 µg to be adequate). Its also best not used for long periods of time. Body homeostasis seems to negate the excitatory and inhibitive functions of clenbuterol over time, creating a complacency effect. It loses most of its nerve stimulation and fat burning benefits after 3-4 weeks, and using it longer on end would be futile. The user is best to discontinue use for an equal period of time and then recommence again.

Another thing people should be aware of is the inherent liver toxicity associated with clenbuterol use. When stacking with oral 17-alpha-alkylated steroids, accutane, anti-biotics or other hepatoxic elements, one should have his liver values checked by a licensed physician at regular points in time to avoid all problems. If you not a yellow discoloration of the skin cease use immediately and contact your doctor.

Clenbuterol should be built up and tapered off gradually with dosage increases and decreases every 3-4 days and doses never exceeding 160 µg per day to be perfectly safe. Its mostly used for periods of 2-3 weeks then discontinued for equal periods of time to disallow the body to adapt to the effects of the drug. For fat-burning goals clenbuterol is often stacked with another fat-burning agent for quick effect, or alternated with another fat-burning agent by people who need to stay lean on a year-round basis. Usually cytomel (T3) is used for such purposes, with alternating cycles of 3 weeks each. If used together, cycles will not completely overlap, but differ slightly so as not to match the low doses with the low and the high doses with the high. A typical cycle for clenbuterol might be 3 weeks, with the daily amounts being 40/40/40/60/60/60/80/80/80/100/100/100/80/80/80/60/60/60/40/40/40 µg/day. Then stopping for three weeks and recommencing.

It's also commonly stacked with anabolic steroids. Usually non-aromatizing steroids that give the user a leaner and harder look, and allow for less water retention. They serve a main purpose of allowing the user to keep as much of his hard-earned muscle mass as he tries to shed the fat he has stocked up in the off-season with catabolic precursors such as clenbuterol. Clenbuterol is generally regarded as fairly safe6, hence its wide-spread use. It should be disadvised for all with blood pressure and/or previously diagnosed cardio-vascular problems. But most tolerate it quite well. By building up the dose over time they usually see when they've reached a dose that becomes too harsh. The use of clenbuterol will elicit higher body temperature, higher blood pressure and in some, especially at high doses, insomnia and jitters. Though these should not be nearly as pronounced with clenbuterol as they are with ephedrine and its legal counterpart ma huang. They are also easily remedied by shifting doses around so you don't take clenbuterol in the hours leading up to bedtime and most of it in pre-training phases when the drug can enhance your training vigor. Another good match for clenbuterol in a stack is the plant derivative yohimbine Hcl. It does concern the standardized product yohimbine here and not the raw material yohimbe, which is useless. In small doses of 20-30 mg per day, it can stop the down-regulation of the noradrenaline feedback mechanisms, that usually inhibit the actions of noradrenaline by reducing receptor affinity. This has two important uses. The first is that the length of action of clenbuterol can be enhanced by a few hours when using it together with yohimbine Hcl (although it already has a considerable half-life time7 of 36 hours and one daily dose should suffice) , and the second is that concomitant use of yohimbine Hcl may allow clenbuterol to induce its fatburning aspects on a longer term than the normal 2-3 weeks, so it can be used for 5-6 weeks instead. Yohimbine Hcl is, at least for now still, a legal supplement that can be acquired for very little money from legal sources and supplement companies.

[theboss]

pretty much summed it up

[MMASTAR]

it works...fast..

[bongd]

Overrated. Ephedrine does the trick and it's shorter acting. Ephedrine also kills my appetite. Clen cranks my metabolism but my appetite seems to speed up too.

If I could tolerate it well, I'd maybe consider using it while lean bulking but I don't know. Little two-week mini cuts with EC work great. To each his own. Most will agree that it's been a little overrated.

[david18]

thank you for that lengthy explanation. it helped a lot. i dont know if this is allowed or not..but were can i get clenbuteral? and what time of day is best to take the pills? right before my workout? right after? or some other time? and i dont want to stack any pills. im completely new at this, would just using clen alone render the same results of losing weight and gaining muscle?

[Praetorian]

Please take the information in the above article with a grain of salt. There are many incorrect assumptions and much misinformation in the article.

1. clen is not catabolic in fact quite the opposite it will preserve muscle which is why is it used in conjunction with T3 and during PCT

2. clen does NOT raise blood pressure in fact it actually lowers blood pressure thus your heart will beat slightly faster in order to counter this effect and bring blood pressure back to normal limits

3. clen is not anabolic in humans or in other words it does not build muscle, that effect has been proven only in animal subjects never in humans

4. dosages need not go over 120mcg and should be raised much slower to counter the attenuization effect...ie every two weeks

5. clen is not a stimulant and doesnt affect the CNS like non specific beta agonists do...ie ephedra, caffeine etc clen is a specific beta 2 agonist which means it only affects beta 2 cells...ie not the heart beta 1

6.clen is effective at lipolysis for 16 weeks if ramped up correctly, there is no need for two weeks on two weeks off cycling etc...just because you dont feel the sides ie jitters doesnt mean its stopped working

6. if you were to measure lipolysis clen has been proven to be much more effective than ephedra without the side effects such as edrenal fatigue, increased cortisol production, CNS stimulation, cardiac issues etc that ephedra is plagued with

P

[Praetorian]

thank you for that lengthy explanation. it helped a lot. i dont know if this is allowed or not..but were can i get clenbuteral? and what time of day is best to take the pills? right before my workout? right after? or some other time? and i dont want to stack any pills. im completely new at this, would just using clen alone render the same results of losing weight and gaining muscle?

Clen has two purposes one to assist in lipolysis (fat burning) and two to preserve lean mass. Thus there are two specific times to use clen effectively...while dieting and while on PCT. You will NOT gain muscle and lose fat using clen. To use it correctly the dose should be divided up throughout the day...even though the half life is 36 hours it has been show this way is best to avoid sides. Start with 20mcg twice per day taken once on the morning and once in the afternoon...increase the dose by 20mcg every two weeks until you hit a maximum of 120mcg daily...this should take 8 weeks. Depending on the length of teh diet leave the dosage at 120mcg and then taper off after the diet is finished.
P

[#8]

how hard is it to sleep on clen? i always had trouble getting quality sleep on just ephedrine / caffeine. is clen worse / better for this?

[Praetorian]

how hard is it to sleep on clen? i always had trouble getting quality sleep on just ephedrine / caffeine. is clen worse / better for this?

Ive taken clen before bed and slept like a baby...but it is not something i would recommend.
P

[Neavris]

Please take the information in the above article with a grain of salt. There are many incorrect assumptions and much misinformation in the article.

1. clen is not catabolic in fact quite the opposite it will preserve muscle which is why is it used in conjunction with T3 and during PCT

2. clen does NOT raise blood pressure in fact it actually lowers blood pressure thus your heart will beat slightly faster in order to counter this effect and bring blood pressure back to normal limits

3. clen is not anabolic in humans or in other words it does not build muscle, that effect has been proven only in animal subjects never in humans

4. dosages need not go over 120mcg and should be raised much slower to counter the attenuization effect...ie every two weeks

5. clen is not a stimulant and doesnt affect the CNS like non specific beta agonists do...ie ephedra, caffeine etc clen is a specific beta 2 agonist which means it only affects beta 2 cells...ie not the heart beta 1

6.clen is effective at lipolysis for 16 weeks if ramped up correctly, there is no need for two weeks on two weeks off cycling etc...just because you dont feel the sides ie jitters doesnt mean its stopped working

6. if you were to measure lipolysis clen has been proven to be much more effective than ephedra without the side effects such as edrenal fatigue, increased cortisol production, CNS stimulation, cardiac issues etc that ephedra is plagued with

P

You're amazing. I'm saving your posts for future references lol...

[Kaly11]

You're amazing. I'm saving your posts for future references lol...

x2 P really knows his shit

[grader]

how hard is it to sleep on clen? i always had trouble getting quality sleep on just ephedrine / caffeine. is clen worse / better for this?

im on day two of my clen " cycle " first time every usiing it, i feel like im a ****ing humming bird for most of the day but then after about 10-12 hours its not so bad and by the time im ready to goto sleep its not a problem

[bluesteal]

i have taken both clen and ephedrine. ephedrine does not even compare to clen....i felt like i was on crack. the only thing that i had a problem with is that i got probably the worst leg cramp i have ever had on my leg day ( i had aprox 1.5L of water well before workout.) someone told me that it has similar effects to a diuretic. this cramp was at about 1 week of use.

[kloan]

So clen is better used during PCT?

How effective would it be during a cruise of 250mg/wk Test E and 40mg anavar for 8 weeks?

[rated_rko]

eca im immune to now...clen though is still solid stuff i dont cut anymore with these products i tend to lose to much muscle with these products....i rather do a short cutting cycle with winny to maintain size and lose bf

[bluesteal]

clen is very inexpensive and it does work.. i would recommend taking it... if you get like a 50 ml bottle it will last forever

[Muscleguy8]

Any bad side effects to clen? and once ur done a cycle will it b easy to maintain the leanness??
thx

[Praetorian]

So clen is better used during PCT?

How effective would it be during a cruise of 250mg/wk Test E and 40mg anavar for 8 weeks?

Clen is effective for fat loss and PCT. If you were dieting it would be effective with that cycle for fat loss.
P

[Praetorian]

i have taken both clen and ephedrine. ephedrine does not even compare to clen....i felt like i was on crack. the only thing that i had a problem with is that i got probably the worst leg cramp i have ever had on my leg day ( i had aprox 1.5L of water well before workout.) someone told me that it has similar effects to a diuretic. this cramp was at about 1 week of use.

Clen can cause a depletion of taurine in the body which can lead to cramping. It also does have a slight diuretic effect so a loss of electrolytes is also possible...usually sodium. Never supplement potassium unless you know you are deficient...potassium regulates cardiac output...do not fool around with it.
Supplement with taurine, drink plenty of water, do not restrict sodium, repelenish electrolytes after training, use sugar free tonic water...natural source of quinine...helps prevent cramps.
P

[Praetorian]

eca im immune to now...clen though is still solid stuff i dont cut anymore with these products i tend to lose to much muscle with these products....i rather do a short cutting cycle with winny to maintain size and lose bf

You would NEVER lose muscle with clen...it is actually muscle sparing...but it is a very effective fat burner. Winny does not burn bodyfat whatsoever.
P

[bigboy999]

taking it rite now in mornings before cardio, makes me tweak out a bit but by the end of the day im gtg, no prob sleeping. I dont really crash off it either, unlike ephedrine that shit made me feel like a biggest crack fiend then i used to crash brutally. i usually run clen for 3 weeks, start at 50mcg go up to 100mcg ed.

[gregdoucette]

ur better off taking Ripped Freak if your trying to get shredded best fat burner I ever used (longest lasting and most energy) I get more energy from 1ripped freak then an ECA combo without the crash.

[Praetorian]

ur better off taking Ripped Freak if your trying to get shredded best fat burner I ever used (longest lasting and most energy) I get more energy from 1ripped freak then an ECA combo without the crash.

The problem with Ripped Freak is it is a non specific beta agonist stimulant based fat burner which also contains a methyl galllate ester to increase the bioavailability and half life of these stimulants in essence making the CNS stimulation even harsher.
I would really suggest avoiding any type of stimulant based fat burners not just because of the inevitable adrenal stress and eventual fatigue but also the increased cortisol production.
P

[MikeyFXD35]

Please take the information in the above article with a grain of salt. There are many incorrect assumptions and much misinformation in the article.

1. clen is not catabolic in fact quite the opposite it will preserve muscle which is why is it used in conjunction with T3 and during PCT

2. clen does NOT raise blood pressure in fact it actually lowers blood pressure thus your heart will beat slightly faster in order to counter this effect and bring blood pressure back to normal limits

3. clen is not anabolic in humans or in other words it does not build muscle, that effect has been proven only in animal subjects never in humans

4. dosages need not go over 120mcg and should be raised much slower to counter the attenuization effect...ie every two weeks

5. clen is not a stimulant and doesnt affect the CNS like non specific beta agonists do...ie ephedra, caffeine etc clen is a specific beta 2 agonist which means it only affects beta 2 cells...ie not the heart beta 1

6.clen is effective at lipolysis for 16 weeks if ramped up correctly, there is no need for two weeks on two weeks off cycling etc...just because you dont feel the sides ie jitters doesnt mean its stopped working

6. if you were to measure lipolysis clen has been proven to be much more effective than ephedra without the side effects such as edrenal fatigue, increased cortisol production, CNS stimulation, cardiac issues etc that ephedra is plagued with

P

Interesting, I have always read it increases your BP. This could be why my girlfriend felt faint when she stood up fast.

[tiramisu]

Clen, the personal non-scientific answer.

I really don't like the way it makes me feel. It's a not quite an amphetamine feeling that is mentally disturbing. I have tried with good intentions to apply clen for fat loss several times and stopped using it within days each time.

Cardio and Diet management are effective ways of reducing bodyfat into the high single digits. I've never been lower than 10% BF so I can't say what happens after that but clen is really not required for normal fat losss.

[Praetorian]

Interesting, I have always read it increases your BP. This could be why my girlfriend felt faint when she stood up fast.

That is definitely low blood pressure...more common in women as well.
P