Gh and diabetes

[Damonic]

My friend wants to run some gh but he has type II diabetes. Is there risk involved with him running gh? He would be using 3iu a day.

[daande]

My friend wants to run some gh but he has type II diabetes. Is there risk involved with him running gh? He would be using 3iu a day.

It will cure his diabetes.

[Praetorian]

Unfortunately no it wont cure diabetes. As long as he is closely monitoring his blood glucose levels he will be fine.
P

[fit226]

GH raises your blood sugar ten fold therefore you have to do twice as much insulin to combat the highs and that in turn does not allow the GH to peel off the fat...its a non winning situation for diabetics...

[Praetorian]

GH raises your blood sugar ten fold therefore you have to do twice as much insulin to combat the highs and that in turn does not allow the GH to peel off the fat...its a non winning situation for diabetics...

This is completely untrue...GH does not raise your blood sugar..in fact taking exogenous GH will illicit an IGF-1 response from the liver and in effect lower blood glucose levels. This also has nothing to do with lipolysis and how GH burns fat..that is a an effect of the GH itself. Insulin is not required when taking GH whatsoever...the only time insulin would be necessary when taking exogenous GH would be if the individual has become insulin resistant...this is not a common occurence however. Again if the athlete is monitoring their blood glucose levels and eating a proper diet taking GH will not affect them negatively.
P

[Andre]

Growth Hormone Replacement Therapy Induces Insulin Resistance by Activating the Glucose-Fatty Acid Cycle

Margareta Bramnert, Mikael Segerlantz, Esa Laurila, Jens R. Daugaard, Per Manhem and Leif Groop
Department of Endocrinology (M.B., M.S., E.L., P.M., L.G.), University Hospital, S-205 02 Malmö, Sweden; and Copenhagen Muscle Research Centre (J.R.D.), Department of Human Physiology, DK-2100 Copenhagen, Denmark

Address all correspondence and requests for reprints to: Margareta Bramnert, Department of Endocrinology, University Hospital MAS, S-205 +2 Malmö, Sweden. E-mail: margareta.bramnert@skane.se.

http://jcem.endojournals.org/cgi/content/full/88/4/1455

[Praetorian]

The specific study does show that GH can in fact cause insulin resistance...in GH deficient subjects however not in athletes with a normal pulsatile GH level. However it is true that GH has been shown to cause insulin resistance in athletes over the long term....dose dependant and duration dependant as well. The overall effect however after an administration of exogenous GH is lowered blood glucose levels due to the IGF-1 response. Insulin resistance in athetes using exogenous GH is extremely rare...I have yet to see it in ten years and hundreds of clients.
P

[Andre]

The specific study does show that GH can in fact cause insulin resistance...in GH deficient subjects however not in athletes with a normal pulsatile GH level. However it is true that GH has been shown to cause insulin resistance in athletes over the long term....dose dependant and duration dependant as well. The overall effect however after an administration of exogenous GH is lowered blood glucose levels due to the IGF-1 response. Insulin resistance in athetes using exogenous GH is extremely rare...I have yet to see it in ten years and hundreds of clients.
P

Damonic's friend has diabetes... so in this scenario, my advice would be to approach with caution and under medical supervision...

[jsv22]

you sure it's type 2 diabetes, not type 1?
do they use insulin?
what kind of shape are they in? why do they want to take gh?

type 2 diabetes is generally considered a lifestyle disease (however, there are some exceptions to this), if this is the case are they obese/out of shape?
It is also possible to become a type 1 diabetic later in life as well...

[Praetorian]

Damonic's friend has diabetes... so in this scenario, my advice would be to approach with caution and under medical supervision...

Hence my post on closely monitoring blood glucose levels. When it comes to medical supervision he will most likely be on his own. A diabetic athlete using exogenous growth hormone is literally out of scope for the majority of MD's. I would suggest he contact someone who has extensive experience in this field...ie Collette Nelson (Dave Palumbos fiance) she has been diabetic for life and is an IFBB pro as well as a diabetes educator.
He can go to rxmuscle and post on her Q&A.
P

[Damonic]

Thanks for the responces guys. He is type two and uses metaformin to regulate his sugar levels. He is in good shape.