A good HGH and Insulin article

[IronMan]

Where can I find one? There were some really good ones a whlie ago but cannot find any of those articles anymore. Like combining HGH with Insulin and so on. Thanks!

[Praetorian]

Take what you read from most of those articles with a grain of salt...there is much misinformation out there taken as the truth so just beware.
P

[waderow]

Where can I find one? There were some really good ones a whlie ago but cannot find any of those articles anymore. Like combining HGH with Insulin and so on. Thanks!

http://www.basskilleronline.com/hgh-igf-insulin.shtml

HGH + IGF-1 + Insulin - A basic guide


There are volumes of information and studies available about using HGH, IGF-1, and Insulin, but for the most part coming up with a good cycle including all of these is a tedious process and requires more reading than most people wish to do or have the time to do. The following is meant to a quick and simple reference to what a cycle including all three might look like and a brief description of the action of each component.

THE CYCLE
Weeks 1- (20-30) - HGH - On 5/ off 2
2 - 2.5 IU's first thing in the morning
2 - 2.5 IU's early afternoon
injected Sub-C into abdomen, obliques, fronts of the thighs, upper triceps

Weeks 1-5, 11-15, (21-25) - Long R3 IGF-1 - Every day
60mcg's intramuscular post work out on workout days,
first thing in the morning on non workout days

Weeks 6-10, 16-20, (26-30) - Humalog - Workout days only
8IU's immediately post workout, intramuscular
*** alternatively, you could run the Humalog on 1-5, 11-15, (21-25) with your LR3 if you prefer, depending on your cycle goal***

Immediately after Humalog injection - do the following
Injection + 5 minutes - drink shake with 10g glutamine / 10g creatine / 55g dextrose
Injection + 15 minutes - drink shake with 80g of whey protein in water
Injection + 60 - 75 minutes - eat a protein / carb meal with 40-50g of protein, 40-50g of carbs, NO FATS
Avoid fats for 2-3 hours for Humalog IM, 3-4 hours for Humalog sub-q, 4-5 hours for Humulin-R.
**keep some glucose tablets or other simple carbs on hand for the active window of your insulin. Hypo symptoms can and will hit hard and fast and you will have little time to react. This is the main danger of insulin use. Be ready.***

OPTIONAL
T3 - 12.5mcg per day (or 12.5mcgs ->100-150mcgs ->12.5mcgs if used for fat loss instead of protein synthesis assist)


HGH
HGH should ideally be used for 20-30 week cycles (or longer). The dosage should be between 2-3IU per day if you are using GH primarily for fat loss, 4-5 IU's a day for both fat loss and muscle growth, and approximately 1.0 - 2.0 IU's a day for females. It is best to split your injections 1/2 first thing in the morning, 1/2 early afternoon if your dose is above 2.0IU's per day. Your pituitary will naturally produce about 10 pulses of GH per day. Each injection you take will create a negative feedback loop that will suppress these pulses for about 4 hours. By taking your injections first thing in the morning and early afternoon you will still allow your body to release its biggest pulse, which normally occurs shortly after going to sleep at night.

When starting out with your HGH cycle, for most people it is wise to begin you dose at 1.5 - 2.0IU per day for the first couple of weeks, and then begin increasing your dose by 0.5 to 1.0 units every week or two until you reach your desired level. While it isn't an absolute necessity to do this, if you are sensitive to the type of sides HGH present you will often times avoid these sides of joint pain/swelling, and bloating/water retention by slowly acclimating to your ultimate 4-5 IU's /day goal.

You should use an U100 insulin syringe for injecting HGH, and inject it Sub-C into your abdomen, obliques, top of thighs, triceps. Rotate injection sites. HGH can have a small localized fat loss benefit, so keep this in mind when choosing your injection sites.

IGF-1
When HGH makes it pass through the liver, a release of IGF-1 is a result. IGF-1 appears to be the key player in muscle growth. It stimulates both the differentiation and proliferation of myoblast. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. While HGH will cause an increase in your IGF-1 level over the course of a few months, HGH has a cumulative effect, so the addition of IGF-1 will greatly speed up the time to results.

There are two types of IGF-1 that will typically be used by bodybuilders. One is bio-identical HuIGF-1, a 70 amino acid string. The other is Long R3 IGF-1, which is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus (hence the long). Which of these you use depends on your goal.

HuIGF-1 is very short lived in the body (half life of probably around 10 minutes). This type of IGF-1 is very useful if you are seeking local site growth. Since it is so short lived, little of the IGF-1 makes it to other tissues and IGF-1 receptors in the body. The way to inject this is immediately post work out into the muscle that you wish to have local site growth. Use a U100 insulin syringe, and inject 80mcg's bilaterally into the desired muscle immediately post workout. For this type of IGF-1, I would use it workout days only or if desired you could inject on non-workout days first thing in the morning into a muscle group worked the previous day.

For Long R3 IGF-1, it isn't as critical that you inject into a local site as long R3 has a active window of many hours, and is designed specifically to resist being bound. Since it is common to reconstitute this type of IGF-1 with Benzyl Alcohol, Acetic Acid, or Hydrochloric Acid I would still recommend that you inject intra-muscular. It can and probably will leave a nice red irritated spot if you inject Sub-C. I still inject into a muscle just worked to take advantage of increased IGF-1 receptors, but because of the long activity window of this type of IGF-1 any muscle will work well and give you good results,. I would suggest that you inject between 40-80mcg's per day everyday immediately post workout on workout days, and first thing in the morning on non-workout days.

Use a U-100 insulin syringe with 1/2" needle to inject IGF-1 intramuscular (bilaterally for HuIGF-1, bilaterally optional for Long R3)


Insulin
Working out causes us to end up in a catabolic state. It is important to back in a positive nitrogen balance as soon as possible. When not using insulin, we drink some dextrose with our protein to cause an insulin spike immediately post workout to help shuttle the protein and sugars to the muscles.

Insulin is very good at shuttling nutrients to the muscles, and works in a very complimentary manner with GH in the types of things that they shuttle. Also, HGH can cause an amount of insulin resistance, so adding some insulin to your cycle will offset any potential resistance that might occur during your HGH cycle.

For the purposes that we are using insulin, a dosage of 4-10IU's is adequate and should be used immediately post workout. I personally prefer using Humalog intramuscular as it will cause a rapid spike and clear out of your system quickly. You can use it sub-q or use Humulin-R instead, but each of these will result in a longer active window, thus a longer time to avoid eating any fats and watching your carb intake. Any fats or over abundance of carbs will end up being stored as fat during insulin's active window. The approximate windows are:
Humalog
Intramuscular ---- 2-3 hours
subcutaneous --- 3-4 hours
Humulin R
Intramuscular ---- 3-4 hours
subcutaneous --- 4-5 hours

Use a U-100 insulin syringe with 1/2" needle to inject IM immediately post workout. Alternatively, you can inject Sub-C if desired or if you wish a longer active window for some reason. Begin with a dose of 2IU's or so, and increase the dose each workout day until you reach your 8IU's.

If for some reason you wish to avoid insulin, I would still suggest that immediately post workout you spike you own endogenous insulin by drinking 80 grams of dextrose / 40 grams of whey isolate protein. While this certainly won't do the work of 8-10 IU's of Humalog, it will most certainly assist getting your muscle back in a nitrogen positive environment in a short amount of time.
T3
HGH can have a slight inhibitory effect on your thyroid. For most people this is minimal and does not require any additional thyroid be taken, but if you wish to augment protein synthesis as well as give yourself a slight boost in thyroid without shutting down your own production, you can add 12.5mcg of T3 daily to your HGH, IGF-1, Insulin cycle. This will aid both in bulking and cutting.

If you add this, you should also consider taking some thyroid support supplements such as t-100x, bladderwrack, coleus forskolin. You should check and make sure your intake of trace minerals (selenium, zinc, copper) is sufficient to aid in the conversion of T4 to T3.

If you are going to take more than 12.5 mcg of T3, you will need to cycle the dose both up and down to avoid a rebound effect when going off cycle, but for our use with an HGH cycle and use in assisting with protein synthesis, 12.5mcg will be sufficient. If you wish to use T3 in conjunction with the above for heavy cutting, begin with 12.5mcgs, ramp up to 100-150mcgs, then slowly back down tapering back to 12.5 mcgs for a time before discontinuing use. This will minimize the chance for rebound while your own thyroid gets back in gear.

Well, I think that about covers it. add a cycle or two of your favorite testosterone and you have a great combination for bulking or cutting.

By RED BARON

[waderow]

http://www.basskilleronline.com/hgh_manual.shtml


Growth Hormone Manual


by Death on the field
With special thanks to Ironmaster's for all his HGH Knowledge and words

this is an article on GH I have been working on, it takes all the advice from the top vets on Growth hormone and has been thoroughly checked and also provides citing so u can look at the info and studies yourself if u want. this was made to benefit all who are looking into starting GH or need basic info on it. i am not trying to take credit for it since most of the ideas in here are either common knowledge or by MOD or Ironmaster, this is only till ironmaster can get a book out with all his info on it. If anyone has anything to add to it please do so, its only to help out the iron brotherhood, enjoy, and merry xmas

Human Growth Hormone

Rating: (1 being the lowest, 5 being the highest)
Strength-4
Weight Gain-4
Fat Loss-4
Side Effects-2
Keep Gains--4

Side Effects:
Hypoglycemia- due to lowered insulin levels.
Aromeglia- (abnormal bone growth) GH does not cause it, but if you are predisposed to it, it will speed it up.
GH gut- if predisposed and taking large doses of GH
Carpel Tunnel Syndrome
Soreness in Joints

Benefits of GH:
New Muscle Cells
Mood Enhancement
Smoothing and improving the skin
Leanness, it is a potent fat burner
Joint and ligament strengthening

Where to Inject, How, and How to Make:
You can site inject anywhere you can reach the subcutaneous layer. Pinch the flesh and pull back, then insert the needle in the "pocket" underneath. Doesn't absorb quick enough if you inject into the adipose tissue. Do not inject intra-muscular, though it can be done, it is not recommended. GH is a site injection, where it is shot is where it will burn the most noticeable fat. Most people do it in the stomach since that is a typical sub q shot with most of the fat being in that area. GH should be kept in a fridge; freezing will destroy the GH. On your kit it probably says to use the kit in 18-24 hours, remember these are for AIDS patients, not bodybuilders or athletes. Mixing the GH can either be done with sterile water or bacteriostatic water. The kit with water will be fine for 3 days in the fridge, even with the sterile water, but you should not take this chance, rather you should use bacteriostatic water and play it safe. This will keep it fine for a couple of weeks. When mixing the GH, let the water slide down the side as to not pulverize the GH wafer. Do not spray it directly against the wafer with any force. Before reconstitution and even after GH is fragile!!! Also once the water is injected into the bottle gently swirl the vial to reconstitute, do not shake or swirl violently!!!!

Conversions:
1 ml = 1 cc -/+
100 units per 1 cc

6 mg = 18iu

1 ml = 18iu

.50 ml = 9iu

.25 ml = 4.5iu

Some people choose to only do it in cc's but here is how you can do it in units on a slin dart

5.5 = 1iu, so 2iu = 11 on a slin dart

Differences Between Kits:
The main difference between kits is how many IU's they make when reconstituted. For example, Serostim re-constitutes to make 126iu, while a Saizen kit.... also made by Serono.... makes up 15iu. Another of their kits makes 54iu. It better be way cheaper than a Serostim kit! Humatrope is fine, but costs too much. The other main concern would be fakes; Lilly is the most often faked one. Some older GH kits do not have holograms on them and are legit, but they are usually only less than 100 dollars than new GH kits with holograms, and I would rather be assured of the hologram and legitimacy of the kit. Best buy currently is Serostim 126 iu kits. These are made for people with wasting diseases like AID's. Many of these patients got infected because they are IV drug addicts..........they sell the Serostim on the street for drug money.


Dose:
4 to 6 i.u ed is sufficient. Most people take it 5 days on 2 days off at their designated dosage. There is no reason or evidence why you cannot stay on for various lengths of time; there is no need to go 5 on 2 off other than cost. Considering that our natural production is only .5 to 1.5iu a day, this is still a huge bump for the body. Research has shown that the body's natural defense systems render mega doses of GH ineffective, anyway. GH does not cause gains in mass...it allows you to put on a great deal of lean mass in combination with proper steroid and insulin use. The user before taking must know this. One or two kits are not enough, you need at least 3 to make you happy, GH takes a while to make its effects, but remember they are long lasting, what you see is what you keep. It takes 6 to 8 weeks to notice a dramatic change in body comp using GH on an ED or 5/2 split. Lighter doses for long periods of time are better than large doses for short cycles. Like any other drug, the more you take the more the benefits, but likewise also more risks. 4-6 i.u is a standard dose but many people take more, the most repulsing side effects happen at or beyond 12 i.u a day but like anything else it depends on your predisposition for it.


How to Stack:
GH is best taken in conjunction with insulin, anabolic steroids, and t3. Insulin is extremely effective with GH, as anyone here who has tried it will testify. This is because GH injections cause a down regulation of insulin sensitivity in the body.
GH alone causes little growth of lean mass, however, when combined with insulin and steroids (and IGF-1 if you can find it), the results can be down right remarkable...esp. in the older bodybuilder. Start light with the Humulin...5iu...and work up 1 iu a day till you get use to it. 7 to 10iu in the AM and 7 to 10 i.u in the late afternoon, with split doses of GH is your best bet. When splitting GH/insulin doses, I use mid-morning and late afternoon after lifting.... both flat times in our natural GH production. The insulin overcomes the insulin-resistance caused by exogenous GH supplementation. If you are scared to take insulin thought, then GH with Test and Glucophage is good. GH is good for cutting if used alone. Glucophage allows for improved glucose and amino acid absorption by the muscle tissue and does it safely. This is what you want. The half-life of GH is only 2 hours so spread it out. Avoid bedtime injections since we produce the bulk of our own GH in the first two hours of sleep. Since exogenous GH suppresses this, you should not take it before bed. For best results, use a 17aa oral during the cycle to stimulate the release of natural insulin growth factors. I would run the test throughout. GH/insulin/test is the proven synergistic combination.
It is also wise to preload with testosterone before starting GH if you are going to do it. You should preload with the amount of time it takes for that testosterone to kick in, since most of us take longer acting esters for testosterone you should usually start taking the test 2 weeks before GH use. Likewise, you can accommodate it to fit your needs; the key is for the test to be kicking in the same time you are starting to run your GH. You can cycle you steroids however you want to depending on your goals, if you are going for a more massive look than you would run insulin for most of the cycle and use high androgens, but if you are looking for additional leanness at the end of a cycle you should stop the androgens and run a higher dose of GH or run less androgens. T3 is also another substance that should be used during human growth hormone cycling since GH lowers thyroid hormones. T3 should be used for shorter periods though, because it can permanently alter the endocrine system. The magic of GH for men is the ability to gain mass without fat or bloating when stacked properly with insulin, and steroids. GH also makes for amazing improvements in skin...smoothes wrinkles, burns stubborn spots of adipose tissue, gives that paper-thin contest look...and also gives one a real mood lift, a feeling of well being.

Major Difference Between GH and Steroids:
Steroids can increase the size of your muscle cells, but cannot I repeat CAN NOT increase the number of muscle cells in your body, which to start with is governed by your genetics. However Growth hormone CAN increase the number of muscle cells in your body, which goes beyond genetics.

Half-Life of GH:
Exogenous (injected) GH has a "half-life" of approximately 2 hours . . . a 4-hour period of activity during which there is a suppression of naturally produced GH.

GH Naturally Produced:
We release the most of our naturally produced GH during the first two hours of deep sleep...you may take a little time to adjust.... your body thinks you should be in bed when that big influx hits. It is good to take a nap, that's when you grow anyway. It always helps to take naps after workouts and injections everyday.

GH Causing Acromeglia:
Acromeglia is a disease...you either have it or you don't. Supplementing growth hormone will not cause it. Persons suffering from acromeglia, like Andre the Giant, lack the natural defense mechanisms of the body to regulate the production and effects of GH secretion in he pituitary. It is well established in the medical literature that exogenous GH will not cause the disease.... of course it would worsen the condition in those who had it.

GH Gut: Myth or Reality?:
Some researchers claim that any gains in weight experienced by subjects using growth hormone alone was due to growth of internal organs and connective tissue, which could cause some problems. Most studies do not agree with this theory and consider "GH gut" to be a myth. Some people are allergic to synthetic test, this is something you have to find out for yourself. Some people also feel intestinal discomfort from time to time, if so take it down to one item at a time to see what is causing you discomfort; creatine, glutamine, protein products, orals, and dirty gear have all been known to cause this, so find the problem early.

GH and IGF-1:
Perhaps the most relevant effect of IGF-1 is the ability of IGF-1 to increase protein synthesis by increasing cellular mRNA formation (mRNA makes protein) as well as increasing uptake of amino acids. This effect on protein synthesis can lead to increased lean mass. The research indicates that this effect is dependent on GH presence as well. So IGF-1 alone does not promote such effects. Nor does GH. It appears the combination of the two most consistently lead to increased protein synthesis.

GH and IGF-1 are negative regulators of growth hormone release so an increase in either (from a GH injection) reduces the secretion of GH. IGF-1 is very difficult to obtain in a useable condition.... it must be handled very gently and have bee kept at a rather precise temperature at all times. One can stimulate IGF production through the use of an oral steroid during cycle. Dianabol, for example, causes a rather extensive release of IGF during the first pass through the liver.

The leading studies in this area: (Ney, 1999, Yarasheski, 1994.... Am J. App. Phys.)
In the Yarasheski study, no increase in lean muscle mass was noticed in the subjects using GH alone, but significant gains were found in subjects that supplemented with IGF and GH...add in the steroids and look out! Yarasheski studied weight trained athletes, supplementing one group with GH alone, and one group with GH and IGF. "So IGF-1 alone does not promote such effects. (Leanness and increased lean mass) Nor does GH. It appears the combination of the two most consistently lead to increased protein synthesis." Both seem to negatively downregulate the other over time, so as to lead to diminishing returns. Cycling would be in order for that reason. Also supplementing both is necessary because one or the other alone will suppress the natural production of the non-supplemented Latest study by Yarashevski - with GH alone...8 to 12% change in lean body composition. 6% increase in muscle mass.

[waderow]

there are millions.... P has a point.

[Praetorian]

As waderow concurred just beware...even in the above articles there is much misinformation.
P

[IronMan]

Thanks guys. Yah I guess I need to ask a good trainer for personalized fine tuned advice on GH and Slin use. I already knew this, but just wanted to know where those good articles went on them. Like one article was called "The Skinny On Slin" I think.