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View Full Version : Overwhelm by BP supplement.



Memo
04-10-2009, 02:46 AM
L-Theanine, Taurine, Hawthorne berry, CoQ10, Garlic.

I have some studies on Taurine, most people tell me to take hawtorn berry extract, I am actually taking 1500mg 3 time a day and started to feel some pressure on my chest, might not be related.

I really want to make sure I am doing the best for my cardio. I am really starting to think that Taurine/L-Theanine combo would do better than CoQ10/Hawthorn like I am doing right now.

Treatment of hypertension with oral taurine: experimental and clinical studies (http://www.springerlink.com/content/vhqev3byr3t2rcbd/)
J. D. Militante and J. B. Lombardini

Summary. Oral taurine treatment has been studied extensively as a hypotensive agent. Several rat models of hypertension have been used to prove that dietary taurine supplementation can alleviate high blood pressure, among other cardiovascular problems. Experimental models mentioned in this review are the spontaneously hypertensive rat, the DOCA-salt rat, the Dahl-S rat, the renovascular hypertensive rat, the hyperinsulinemic rat and the ethanol-treated rat. The beneficial effects of taurine were also demonstrated in studies involving human subjects suffering essential hypertension. Taurine supplementation of 6 g/day for as little as 7 days resulted in measurable decreases in blood pressure in these patients. In both rat and human studies, the effects of taurine appeared to be dependent on the modulation of an overactive sympathetic system. However, taurine has positive effects on other types of cardiovascular problems and thus may act through more than one mechanism.

Taurine lowers blood pressure in the spontaneously hypertensive rat by a catecholamine independent mechanism. (http://www.ncbi.nlm.nih.gov/pubmed/2610995)
Trachtman H, Del Pizzo R, Rao P, Rujikarn N, Sturman JA.

Taurine, a sulfur aminoacid, has been studied for a role in blood pressure regulation since it functions as a generalized inhibitory neurotransmitter and is found in high concentrations in the myocardium. We reinvestigated the magnitude of the hypotensive effect of chronic taurine administration to the spontaneously hypertensive rat (SHR) and the role of catecholamines in such an action. The SHR received either a 1% taurine solution or tap water to drink for 16 weeks. Taurine treatment caused a significant persistent reduction in blood pressure by 4 weeks that was maximal at 16 weeks (146 +/- 6 [exp.] v 182 +/- 5 [control] mm Hg, P less than .01). While this taurine-induced decline in blood pressure in the SHR was not accompanied by alterations in plasma epinephrine levels, there was a steady 235% increment in the norepinephrine concentration from 231 +/- 31 pg/mL initially to 542 +/- 126 pg/mL at completion of the study, P less than .02. The reduction in blood pressure was associated with decreased proteinuria in the taurine-treated SHR (9.6 +/- 4 [exp.] v 21.5 +/- 7 [control] mg/24 h, P less than .02) and less cardiac and renal hypertrophy. We conclude that taurine administration results in a 20 to 25% reduction in blood pressure in the SHR. The mechanism of this hypotensive action requires further study but is independent of changes in plasma catecholamine levels. The vasodepressor effect of taurine leads to less hypertensive injury to the kidney and heart in the SHR.