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MMASTAR
02-10-2009, 10:52 PM
im a little slow on this subject so bear with me,,, peptides are normally injected corect?? what about taking them oraly? what is the normal dosage for peptides? found this:

Tulane University Medical Center, New Orleans, LA 70112.

A new class of small synthetic peptides has been developed which specifically release GH. They consist of 6-7 amino acids and release GH in animals as well as humans. So far 3 of these peptides have been administered to humans, i.e., GHRP-6, GHRP-1 and GHRP-2. As in rats, these 3 peptides have been found to be increasingly more effective in releasing GH in humans. All 3 GHRPs release GH more efficaciously than GHRH 1-44 NH2 in humans. Particularly note-worthy is that GHRP-6, GHRP-1 AND GHRP-2 all release GH after oral administration. Near maximal amounts of GH can be released after GHRP-1 and GHRP-2 oral administration. In the present studies, the GH responses and serum irGHRP levels after i.v., s.c. and oral administration have been determined in normal younger men and/or women. By each route of administration GH was very effectively released. Additionally, GH release was induced by oral GHRP-6 in children with various degrees of GH deficiency. Noteworthy is the synergistic release of GH induced by the combined i.v. bolus administration of 1 microgram/kg of GHRP-1 + GHRH 1-44NH2. Thus, these results demonstrate GHRPs' potential importance at the theoretical as well as pharmaceutical level.

MMASTAR
02-10-2009, 11:13 PM
Growth hormone has a brief half life and is rendered ineffective when orally applied, swallowed and passed into the gastric tract. Then it must pass through the liver when applied orally. This is why HGH is effectively administered through subcutaneous injections. Conversely, GHRP2 oral mucosal medicine delivery i.e.: sublingual/ intranasal as demonstrated in clinical studies, is an effective alternative method of systemic medicine /supplement delivery that offers not only impressive results -- but several advantages over both injectable and enteral methods.



Because the oral mucosa is highly vascularised, medi-suppliments that are absorbed through the oral mucosa directly enter the systemic circulation, bypassing the gastrointestinal tract and first pass metabolism in the liver. For some supplements and drugs, this results in rapid onset of action via a more comfortable and convenient delivery route than the intravenous route. Not all medications, however, can be administered through the oral mucosa because of the characteristics of the oral mucosa and the physicochemical properties of the supplement.



GHRP2 can be delivered sublingual and is the preferred method of application -- and in a peer reviewed clinical study from the Department of Pediatrics at the University of Arkansas for Medical Sciences, published in the Journal of Endocrinology and Metabolism in 1995, "All 15 children had a significant GH response to 15 pg/kg dose. The intranasal /mucosa delivery was well tolerated."

MMASTAR
03-10-2009, 05:15 AM
Effective dosages in humans range from 100mcg to 3mcg/Kg of body weight ????

http://www.musclesci-store.com/ghrp2-p-50.html

CMS Pimp
03-10-2009, 09:46 AM
GHRP2 is orally available, but you need a lot more to have the same effect, which makes it inneficient.

MMASTAR
03-10-2009, 12:51 PM
GHRP2 is orally available, but you need a lot more to have the same effect, which makes it inneficient.

not what ive read from several studies...

hyperlite32
03-10-2009, 01:40 PM
what would be the posatives/negatives to oral use VS injection? timing, dose, amount?

cog
03-10-2009, 01:42 PM
what would be the posatives/negatives to oral use VS injection? timing, dose, amount?

The general population doesn't mix with sub-q.Can't find it at the moment,I recently viewed the page of an anti-ageing clinic that offered sublingual GHRP-2.

MMASTAR
03-10-2009, 01:46 PM
timing mostly...and maybe im not fan of needles..lol